New pill combo aims to crush high cholesterol

NCT ID NCT07444762

Completed Disease control Sponsor: Daewon Pharmaceutical Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 3 trial tested whether taking two cholesterol-lowering drugs together works better than one alone. 184 adults with high cholesterol or mixed dyslipidemia took either the combo or a single drug daily for 8 weeks. The main goal was to see how much LDL ('bad') cholesterol dropped.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: DW5421A and DW5421B (two cholesterol-lowering drugs taken as pills)
What this could lead to: If successful, this combination could offer a more effective way to lower LDL cholesterol than using one drug alone, potentially reducing heart disease risk.
What could go wrong: This is a completed Phase 3 trial, but results are not yet published. The combination may not be significantly better than the single drug, or could cause more side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hyperlipidemia, familial combined, LPL related

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MIXED DYSLIPIDEMIA PRIMARY HYPERCHOLESTEROLEMIA

Contacts and locations

Locations

Korea University Anam Hospital

Seoul, 02841, South Korea

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