Cancer vaccine trial aims to stop colorectal cancer from coming back

NCT ID NCT04486378

Recruiting now Disease control Sponsor: BioNTech SE Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a personalized cancer vaccine (RO7198457) can prevent cancer from returning in patients who have had surgery for stage II or III colorectal cancer and still have traces of cancer DNA in their blood. The trial will compare the vaccine against a 'watchful waiting' approach, where patients are monitored but receive no additional treatment. The main goal is to see if the vaccine helps patients live longer without their cancer coming back.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

AZ Delta Roeselare
ACTIVE_NOT_RECRUITING

Roeselare, 8800, Belgium
AZ Groeninge
ACTIVE_NOT_RECRUITING

Kortrijk, 8500, Belgium
Allina Health
ACTIVE_NOT_RECRUITING

Minneapolis, Minnesota, 55407, United States
Asklepios Klinik Altona
ACTIVE_NOT_RECRUITING

Hamburg, 22763, Germany
Beatson West of Scotland Cancer Centre - Gartnavel Royal Hospital - NHS Greater Glasgow and Clyde
ACTIVE_NOT_RECRUITING

Glasgow, G12 0XH, United Kingdom
Benaroya Research Institute at Virginia Mason
ACTIVE_NOT_RECRUITING

Seattle, Washington, 98101, United States
Boca Raton Regional Hospital
WITHDRAWN

Boca Raton, Florida, 33486, United States
Cancer Care Center of Decatur, Cancer Care Specialists of IL
ACTIVE_NOT_RECRUITING

Decatur, Illinois, 62526, United States
Centres Hospitaliers Jolimont
ACTIVE_NOT_RECRUITING

La Louvière, 7100, Belgium
Charité - Universitätsmedizin Berlin
ACTIVE_NOT_RECRUITING

Berlin, 10117, Germany
Churchill Hospital - Oxford University Hospitals NHS Foundation Trust
ACTIVE_NOT_RECRUITING

Oxford, OX3 7LE, United Kingdom
Clinica Universidad Navarra
ACTIVE_NOT_RECRUITING

Madrid, 28027, Spain
Clinica Universitaria de Navarra
ACTIVE_NOT_RECRUITING

Pamplona, 31008, Spain
Complejo Hospitalario Universitario A Coruna
ACTIVE_NOT_RECRUITING

A Coruña, 15006, Spain
Complejo Hospitalario Universitario De Santiago De Compostela
ACTIVE_NOT_RECRUITING

Santiago de Compostela, 15706, Spain
Complejo Hospitalario de Navarra (CHN)
ACTIVE_NOT_RECRUITING

Pamplona, 31008, Spain
Complejo Hospitalario de Orense
ACTIVE_NOT_RECRUITING

Ourense, 32005, Spain
Complexo Hospitalario Universitario de Vigo (CHUVI)
ACTIVE_NOT_RECRUITING

Vigo, 36312, Spain
Consorcio Hospital General Valencia
ACTIVE_NOT_RECRUITING

Valencia, 46014, Spain
Dorset County Hospital NHS Foundation Trust - Dorset County Hospital
ACTIVE_NOT_RECRUITING

Dorchester, DT1 2JY, United Kingdom
Florida Cancer Specialist South
WITHDRAWN

Fort Myers, Florida, 33916, United States
Florida Cancer Specialists
WITHDRAWN

West Palm Beach, Florida, 33401, United States
Froedtert Hospital and Medical College of Wisconsin
WITHDRAWN

Milwaukee, Wisconsin, 53226, United States
GHDC (Grand Hopital de Charleroi)
ACTIVE_NOT_RECRUITING

Charleroi, 6000, Belgium
GasthuisZusters Antwerpen - Sint-Augustinus
ACTIVE_NOT_RECRUITING

Wilrijk, 2610, Belgium
Guy's and St Thomas' Hospital NHS Foundation Trust
ACTIVE_NOT_RECRUITING

London, SE1 7EH, United Kingdom
Hollings Cancer Center Medical University Of South Carolina
WITHDRAWN

Charleston, South Carolina, 29425, United States
Hospital Clinico San Carlos
ACTIVE_NOT_RECRUITING

Madrid, 28040, Spain
Hospital General Universitario Gregorio Maranon
ACTIVE_NOT_RECRUITING

Madrid, 28007, Spain
Hospital Nuestra Senora de Sonsoles
ACTIVE_NOT_RECRUITING

Ávila, 05004, Spain
Hospital Regional Universitario Carlos Haya Malaga - Instituto de Investigacion Biomedica de Malaga
ACTIVE_NOT_RECRUITING

Málaga, 29011, Spain
Hospital Universitari Germans Trias - ICO Badalona
ACTIVE_NOT_RECRUITING

Badalona, 08916, Spain
Hospital Universitari Vall d'Hebron
ACTIVE_NOT_RECRUITING

Barcelona, 08035, Spain
Hospital Universitario Fundacion Jimenez Diaz
ACTIVE_NOT_RECRUITING

Madrid, 28040, Spain
Hospital Universitario HMN Sanchinarro, Centro Integral Oncologico Clara Campal (CIOCC)
ACTIVE_NOT_RECRUITING

Madrid, 28050, Spain
Hospital Universitario La Paz
ACTIVE_NOT_RECRUITING

Madrid, 28046, Spain
Hospital Universitario Marques De Valdecilla
ACTIVE_NOT_RECRUITING

Santander, 39008, Spain
Hospital Universitario Miguel Servet
ACTIVE_NOT_RECRUITING

Zaragoza, 50009, Spain
Hospital Universitario Puerta de Hierro de Majadahonda
ACTIVE_NOT_RECRUITING

Majadahonda, 28222, Spain
Hospital Universitario Ramón y Cajal
ACTIVE_NOT_RECRUITING

Madrid, 28034, Spain
Hospital Universitario Reina Sofia
ACTIVE_NOT_RECRUITING

Córdoba, 14004, Spain
Hospital Universitario Virgen del Rocio - Hospital de la Mujer
ACTIVE_NOT_RECRUITING

Seville, 41013, Spain
Hospital de la Santa Creu i Sant Pau
ACTIVE_NOT_RECRUITING

Barcelona, 8041, Spain
Hull and East Yorkshire Hospitals NHS Trust - Castle Hill Hospital
ACTIVE_NOT_RECRUITING

Cottingham, HU16 5JQ, United Kingdom
Hämatologisch-Onkologische Praxis Eppendorf
ACTIVE_NOT_RECRUITING

Hamburg, 20249, Germany
Imeldaziekenhuis General Hospital
ACTIVE_NOT_RECRUITING

Bonheiden, 2820, Belgium
Indiana University Melvin and Bren Simon Comprehensive Cancer
ACTIVE_NOT_RECRUITING

Indianapolis, Indiana, 46202, United States
Institut Clinic Hematolo/Oncologia- ICMHO, Hospital Clinic i Provincial de Barcelona
RECRUITING

Barcelona, 8036, Spain
Institut Jules Bordet
WITHDRAWN

Brussels, 1070, Belgium
John Muir Clinical Research Center
ACTIVE_NOT_RECRUITING

Concord, California, 94520, United States
Josephine Ford Cancer Center-Henry Ford Cancer Center
WITHDRAWN

Detroit, Michigan, 48202, United States
Karolinska Universitetssjukhuset Solna
WITHDRAWN

Stockholm, 17176, Sweden
Klinikum Esslingen GmbH
WITHDRAWN

Esslingen am Neckar, 73730, Germany
Klinikum der Johann Wolfgang Goethe-Universitaet Frankfurt
ACTIVE_NOT_RECRUITING

Frankfurt am Main, 60590, Germany
Klinikum der Philipps-Universität Marburg
ACTIVE_NOT_RECRUITING

Marburg, 35043, Germany
Krankenhaus Nordwest GmbH - Institut Fuer Klinisch-Onkologische Forschung (IKF)
ACTIVE_NOT_RECRUITING

Frankfurt am Main, 60488, Germany
LMU Klinikum (Campus Großhadern) Medizinische Klinik Universität München
ACTIVE_NOT_RECRUITING

München, 81377, Germany
Lunds Universitet - Medicinska Fakulteten (Lund University Faculty of Medicine)
ACTIVE_NOT_RECRUITING

Lund, 221 00, Sweden
Marin Cancer Care
ACTIVE_NOT_RECRUITING

Greenbrae, California, 94904, United States
Mayo Clinic - Scottsdale
WITHDRAWN

Scottsdale, Arizona, 85259, United States
Mayo Clinic Florida
WITHDRAWN

Jacksonville, Florida, 32224, United States
Mayo Clinic Rochester
WITHDRAWN

Rochester, Minnesota, 55905, United States
Medizinische Hochschule Hannover
ACTIVE_NOT_RECRUITING

Hanover, 30625, Germany
MultiCare Institute for Research & Innovation
WITHDRAWN

Spokane, Washington, 99218, United States
National Center for Tumor Diseases (NCT) Heidelberg
ACTIVE_NOT_RECRUITING

Heidelberg, 69120, Germany
New York - Presbyterian Hospital - Columbia University Medical center
WITHDRAWN

New York, New York, 10032, United States
New York Oncology Hematology, P.C.
WITHDRAWN

Albany, New York, 12206, United States
Northwest Cancer Specialists P.C.
ACTIVE_NOT_RECRUITING

Vancouver, Washington, 98684, United States
OhO Ostholstein Onkologie
ACTIVE_NOT_RECRUITING

Oldenburg in Holstein, 23758, Germany
Oncology Hematology Care Clinical Trials
ACTIVE_NOT_RECRUITING

Cincinnati, Ohio, 45245, United States
Princess Margaret Cancer Centre
ACTIVE_NOT_RECRUITING

Toronto, M5G 1X6, Canada
Prosper Hospital
ACTIVE_NOT_RECRUITING

Recklinghausen, 45659, Germany
Queen Elizabeth Hospital Birmingham-University Hospitals Birmingham NHS Foundation Trust
ACTIVE_NOT_RECRUITING

Birmingham, B15 2GW, United Kingdom
Rhode Island Hospital
ACTIVE_NOT_RECRUITING

Providence, Rhode Island, 02906, United States
Robert-Bosch-Krankenhaus - Centrum fuer Tumorerkrankungen
WITHDRAWN

Stuttgart, 70376, Germany
Rocky Mountain Cancer Centers - Denver Midtwon
ACTIVE_NOT_RECRUITING

Denver, Colorado, 80218, United States
Royal Free London NHS Foundation Trust
WITHDRAWN

London, NW3 2QG, United Kingdom
Royal Preston Hospital - Lancashire Teaching Hospitals NHS Foundation Trust
ACTIVE_NOT_RECRUITING

Preston, PR2 9HT, United Kingdom
SLK-Kliniken Heilbronn GmbH
ACTIVE_NOT_RECRUITING

Heilbronn, 74078, Germany
Sansum Clinic
ACTIVE_NOT_RECRUITING

Santa Barbara, California, 93105, United States
Sarah Cannon (Tennessee Oncology - Nashville)
COMPLETED

Nashville, Tennessee, 37203, United States
Sarah Cannon Research Institute (SCRI) Oncology Partners
ACTIVE_NOT_RECRUITING

Nashville, Tennessee, 37203, United States
Sodersjukhuset, Onkologiska Kliniken
ACTIVE_NOT_RECRUITING

Stockholm, 11883, Sweden
St Bartholomew's Hospital-Barts Health NHS Trust
RECRUITING

London, EC1A 7BE, United Kingdom
St Joseph Hospital of Orange
WITHDRAWN

Orange, California, 92868, United States
Staedtisches Krankenhaus Kiel gGmbH
ACTIVE_NOT_RECRUITING

Kiel, 24116, Germany
Studiengesellschaft BSF
ACTIVE_NOT_RECRUITING

Halle, 06108, Germany
Städtisches Klinikum München GmbH, Klinikum Neuperlach
ACTIVE_NOT_RECRUITING

München, 81737, Germany
Texas Oncology - Northeast Texas
ACTIVE_NOT_RECRUITING

Tyler, Texas, 75702, United States
Texas Oncology, P.A. - Austin
ACTIVE_NOT_RECRUITING

Austin, Texas, 78705, United States
Texas Oncology-Baylor Charles A. Sammons Cancer Center
ACTIVE_NOT_RECRUITING

Dallas, Texas, 75246, United States
Texas Oncology-San Antonio Medical Center
ACTIVE_NOT_RECRUITING

San Antonio, Texas, 78240, United States
The Christie NHS Foundation Trust
ACTIVE_NOT_RECRUITING

Manchester, M20 4BX, United Kingdom
The Clatterbridge Cancer Centre NHS Foundation Trust
ACTIVE_NOT_RECRUITING

Bebington, CH63 4JY, United Kingdom
The Newcastle upon Tyne Hospitals NHS Foundation Trust - Freeman Hospital
ACTIVE_NOT_RECRUITING

Newcastle upon Tyne, NE7 7DN, United Kingdom
The Oncology Institute of Hope and Innovation
WITHDRAWN

Glendale, California, 91204, United States
The Ottawa Hospital Cancer Centre
ACTIVE_NOT_RECRUITING

Ottawa, K1H 8M2, Canada
The Royal Marsden NHS Foundation Trust
RECRUITING

Sutton, SM25NG, United Kingdom
The Royal Marsden NHS Foundation Trust- Chelsea
ACTIVE_NOT_RECRUITING

London, SW3 6JJ, United Kingdom
The University of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Torbay Hospital - South Devon Healthcare Nhs Foundation Trust, Lowes Bridge
ACTIVE_NOT_RECRUITING

Torquay, TQ2 7AA, United Kingdom
Universitaetsklinikum Leipzig AoeR
ACTIVE_NOT_RECRUITING

Leipzig, 04103, Germany
Universitaetsklinikum St. Josef-Hospital Bochum
ACTIVE_NOT_RECRUITING

Bochum, 44791, Germany
Universitaetsmedizin der Johannes Gutenberg Universitaet Mainz KoeR
ACTIVE_NOT_RECRUITING

Mainz, 55131, Germany
Universitaire Ziekenhuizen Leuven
ACTIVE_NOT_RECRUITING

Leuven, 3000, Belgium
Universite Catholique de Louvain (UCL) - Cliniques Universitaires Saint-Luc
ACTIVE_NOT_RECRUITING

Woluwe-Saint-Lambert, 1200, Belgium
University College London Hospitals NHS Foundation Trust
ACTIVE_NOT_RECRUITING

London, NW2 1PG, United Kingdom
University Hospital Southampton NHS Foundation Trust - Southampton General Hospital
WITHDRAWN

Southampton, SO16 6YD, United Kingdom
University of Kansas Cancer Center
WITHDRAWN

Westwood, Kansas, 66205, United States
University of Louisville - James Graham Brown Cancer Center
WITHDRAWN

Louisville, Kentucky, 40202, United States
University of Washington
ACTIVE_NOT_RECRUITING

Seattle, Washington, 98109, United States
University of Wisconsin Carbone Cancer Center
ACTIVE_NOT_RECRUITING

Madison, Wisconsin, 53792, United States
Universitätsklinikum Bonn, Med. Klinik u. Poliklinik I
ACTIVE_NOT_RECRUITING

Bonn, 53105, Germany
Universitätsklinikum Hamburg-Eppendorf
ACTIVE_NOT_RECRUITING

Hamburg, 20246, Germany
Universitätsklinikum Ulm
ACTIVE_NOT_RECRUITING

Ulm, 89081, Germany
Universitätsklinikum Würzburg
ACTIVE_NOT_RECRUITING

Würzburg, 97080, Germany
VZW Algemeen Ziekenhuis AZ Klina
ACTIVE_NOT_RECRUITING

Brasschaat, 2930, Belgium
Velindre NHS Trust, Velindre Cancer Centre
ACTIVE_NOT_RECRUITING

Cardiff, CF14 2TL, United Kingdom
Virginia Cancer Specialists
ACTIVE_NOT_RECRUITING

Fairfax, Virginia, 22031, United States
Weill Cornell Medical College
WITHDRAWN

New York, New York, 10021, United States
Willamette Valley Cancer Institute and Research Center
WITHDRAWN

Eugene, Oregon, 97401, United States

Conditions

Explore the condition pages connected to this study.

COLORECTAL CANCER STAGE II COLORECTAL CANCER STAGE III