New combo therapy tested for Tough-to-Treat colon cancer

NCT ID NCT03828799

Summary

This study tested the safety and effectiveness of combining two cancer drug regimens—regorafenib and FOLFIRINOX—for patients with advanced colorectal cancer that has spread and has a specific RAS gene mutation. The main goal was to find the highest dose patients could tolerate without severe side effects. It was a small, early-phase trial involving 13 participants to see if this combination could help control the cancer.

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Contacts and locations

Locations

  • Centre Antoine Lacassagne

    Nice, Alpes-Maritimes, 06189, France

  • Centre Cario - HPCA

    Plérin, Finistère, 22190, France

  • Centre Georges-François Leclerc

    Dijon, Côte d'Or, 21079, France

  • Institut du Cancer de Montpellier - Val d'Aurelle

    Montpellier, 34298, France

Conditions

Explore the condition pages connected to this study.