Could a collagen wrap save your jawbone for better dental implants?

NCT ID NCT07580495

Recruiting now Disease control Sponsor: Debora Dias Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a resorbable collagen membrane to a bone graft helps preserve the shape and volume of the jawbone after a tooth is removed. Thirty adults with a missing front tooth and significant bone loss will receive either the bone graft alone or with the membrane. After about 4 months, scans will measure bone changes to see if the membrane improves outcomes for future dental implant placement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: resorbable collagen membrane (InterCollagen® Guide) and anorganic bone-collagen composite (ABCC, SigmaGraft®)
What this could lead to: If it works, this could improve the success of dental implants by maintaining jawbone shape after tooth extraction, reducing the need for additional bone grafting.
What could go wrong: This is a small, early-stage trial with only 30 participants, so results may not apply to everyone. The collagen membrane may not provide significant benefit over the bone graft alone, and there are risks like infection or poor healing.

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Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALVEOLAR BONE LOSS DEHISCENCE TOOTH EXTRACTION

Contacts and locations

Locations

University of Pittsburgh School of Dental Medicine, Department of Periodontics and Preventive Dentistry
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States

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