Could a collagen wrap save your jawbone for better dental implants?

NCT ID NCT07580495

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a resorbable collagen membrane to a bone graft helps preserve the shape and volume of the jawbone after a tooth is removed. Thirty adults with a missing front tooth and significant bone loss will receive either the bone graft alone or with the membrane. After about 4 months, scans will measure bone changes to see if the membrane improves outcomes for future dental implant placement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

resorbable collagen membrane (InterCollagen® Guide) and anorganic bone-collagen composite (ABCC, SigmaGraft®)

What this could lead to

If it works, this could improve the success of dental implants by maintaining jawbone shape after tooth extraction, reducing the need for additional bone grafting.

What could go wrong

This is a small, early-stage trial with only 30 participants, so results may not apply to everyone. The collagen membrane may not provide significant benefit over the bone graft alone, and there are risks like infection or poor healing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pittsburgh School of Dental Medicine, Department of Periodontics and Preventive Dentistry

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact