Does the amount of fluid in colistin matter for ventilator pneumonia?

NCT ID NCT06230614

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study is testing whether using a smaller or larger amount of fluid to mix the antibiotic colistin affects how well it works in patients on ventilators with pneumonia. Sixty intensive care patients will receive the same dose of colistin but mixed with either 1 ml or 2 ml of saline. Researchers will measure drug levels in the lungs and blood, and track recovery time and side effects like nebulizer clogs.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
colistin
What this could lead to
If successful, this could help doctors choose the best way to give colistin inhalation therapy to ventilated patients, potentially improving treatment effectiveness.
What could go wrong
This is a small, early-stage study (60 people) that only looks at how the drug is prepared, not a new treatment. It may not lead to major changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fu Jen Catholic University Hospital, Fu Jen Catholic University

    RECRUITING

    New Taipei City, 24352, Taiwan

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