Does the amount of fluid in colistin matter for ventilator pneumonia?

NCT ID NCT06230614

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether using a smaller or larger amount of fluid to mix the antibiotic colistin affects how well it works in patients on ventilators with pneumonia. Sixty intensive care patients will receive the same dose of colistin but mixed with either 1 ml or 2 ml of saline. Researchers will measure drug levels in the lungs and blood, and track recovery time and side effects like nebulizer clogs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

colistin

What this could lead to

If successful, this could help doctors choose the best way to give colistin inhalation therapy to ventilated patients, potentially improving treatment effectiveness.

What could go wrong

This is a small, early-stage study (60 people) that only looks at how the drug is prepared, not a new treatment. It may not lead to major changes in care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aspiration pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fu Jen Catholic University Hospital, Fu Jen Catholic University

    RECRUITING

    New Taipei City, 24352, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact