Combination antibiotics show promise against Drug-Resistant pneumonia

NCT ID NCT07671755

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at two antibiotic treatments for ventilator-associated pneumonia caused by a multidrug-resistant bacteria. Researchers compared giving patients just colistin versus colistin plus cefoperazone-sulbactam. They measured how well patients improved clinically and on chest X-rays. The trial included 80 adults with this specific infection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

colistin and cefoperazone-sulbactam

What this could lead to

If the combination works better, it could offer a more effective treatment option for this hard-to-treat lung infection.

What could go wrong

This is a small, completed study with only 80 participants, so results may not apply widely. The drugs can cause kidney or liver problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pneumonia, Ventilator-Associated

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shaheed Mohtarma Benazir Bhutto Institue of Trauma

    Karachi, Pakistan