Could a cold water rinse soothe radiation mouth pain?
NCT ID NCT07252557
First seen Dec 12, 2025 · Last updated Jun 19, 2026 · Updated 26 times
Summary
This study tests whether rinsing with cold water (about 15-20°C) reduces mouth sore pain and improves comfort compared to room-temperature water in head and neck cancer patients undergoing radiotherapy. Two hundred participants will rinse four times daily for six weeks. The goal is to see if cold water can lessen the severity of radiation-induced mouth sores and pain.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Chung Shan Medical University
Taichung, Taiwan (r.o.c.), Taiwan
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
water rinse at different temperatures (cold 15-20°C vs. room temperature 30-35°C)
What this could lead to
If it works, this simple, low-cost method could help reduce painful mouth sores and improve comfort for patients undergoing radiation for head and neck cancer.
What could go wrong
This is a small, early-stage trial with no blinding, so results may be influenced by patient expectations. The effect may be modest and not change standard care.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.