Can a 'Cold Knife' beat heat for polyp removal?
NCT ID NCT07737301
First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time
Summary
This trial tests whether a cold knife hysteroscopy technique (Yiwu procedure) can remove multiple endometrial polyps as effectively as standard electrocision, but with less damage to the uterine lining. About 850 women aged 20 to 48 with multiple polyps will be randomly assigned to one of the two surgeries. The main question is whether the cold knife approach leads to fewer polyps returning within a year, while keeping surgical risks low.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cold knife hysteroscopic polypectomy (Yiwu procedure)
- What this could lead to
- If successful, this technique could offer a safer, less damaging way to remove multiple endometrial polyps, potentially lowering the chance they grow back.
- What could go wrong
- This is an early comparison trial; the cold knife method may not prove as effective as standard electrocision, and could carry different surgical risks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.