Can a targeted cancer drug shrink AVM blood vessels?

NCT ID NCT05125471

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 25 times

Summary

This small study tested the drug cobimetinib in 3 people with arteriovenous malformations (AVMs) outside the brain. The goal was to see if the drug could safely shrink the abnormal blood vessels. Participants took the drug by mouth, and doctors used MRI scans to measure changes in AVM size.

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Contacts and locations

Locations

  • Arkansas Children's Hospital

    Little Rock, Arkansas, 72202, United States

Conditions

Explore the condition pages connected to this study.