Could CO2 be the key to healing stubborn diabetic wounds?

NCT ID NCT04561609

Completed Disease control Sponsor: University Medical Centre Ljubljana Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new way to help heal chronic wounds on the legs or feet of people with diabetes. The treatment involves applying carbon dioxide gas directly to the wound to improve blood flow and oxygen release. 120 adults with diabetes and non-healing ulcers took part to see if this approach speeds up healing and reduces wound size.

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Conditions

The condition(s) this trial relates to.

Foot Ulcer Leg Ulcer ulcer of lower limbs

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC WOUND OF THE LOWER LIMB (LEG ULCER OR FOOT ULCER)

Contacts and locations

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Locations

Clinical Hospital Merkur, University Clinic for Diabetes, Endocrinology, and Metabolic Diseases Vuk Vrhovac, Dugi dol 4a, 10000 Zagreb

Zagreb, Croatia, 10000, Croatia
General hospital Novo mesto

Novo Mesto, Slovenia, 8000, Slovenia
UMCLjubljana

Ljubljana, Ljubljana, 1000, Slovenia