CO2 therapy shows promise for stubborn diabetic wounds

NCT ID NCT04561609

Completed Disease control Sponsor: University Medical Centre Ljubljana Source: ClinicalTrials.gov ↗

First seen Jan 28, 2026 · Last updated May 14, 2026 · Updated 16 times

Summary

This study tested whether applying carbon dioxide gas directly to chronic leg or foot ulcers in people with diabetes can speed up healing. The gas is thought to improve blood flow and oxygen delivery to the wound. 120 adults with diabetes and non-infected foot or leg ulcers took part. The goal was to see if more wounds healed completely and if the wound size shrank faster with this treatment.

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Contacts and locations

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Locations

Clinical Hospital Merkur, University Clinic for Diabetes, Endocrinology, and Metabolic Diseases Vuk Vrhovac, Dugi dol 4a, 10000 Zagreb

Zagreb, Croatia, 10000, Croatia
General hospital Novo mesto

Novo Mesto, Slovenia, 8000, Slovenia
UMCLjubljana

Ljubljana, Ljubljana, 1000, Slovenia

Conditions

Explore the condition pages connected to this study.

CHRONIC WOUND OF THE LOWER LIMB (LEG ULCER OR FOOT ULCER)