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Retraining the brain to turn down neck pain — a new approach put to the test

NCT ID NCT06503562

Symptom relief Sponsor: Acibadem University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial tests whether adding brain-focused therapies — pain education, breathing exercises, and guided relaxation — to standard physiotherapy can better relieve chronic nonspecific neck pain. Researchers will measure changes in pain, movement, fear of pain, and quality of life in 30 adults aged 18 to 65 who have had neck pain for over three months. The goal is to see if teaching the brain to unlearn pain can improve outcomes beyond physical treatments alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
central nervous system focused treatment program including pain neuroscience education, breathing exercises, and relaxation exercises with guided imagery
What this could lead to
If it works, this could point toward a more effective treatment for chronic neck pain that addresses how the brain processes pain, not just the neck itself.
What could go wrong
This is a very small, early-stage trial with only 30 participants, so results may not apply broadly. The added therapies may not provide extra benefit over standard physiotherapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Jul 2024

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Being diagnosed with nonspecific neck pain by a doctor, * To be between the ages of 18-65, * Having neck pain for more than 3 months * No previous neck or shoulder surgery, * No shoulder pain due to any cause, * A tumour or inflammatory disease underlying the neck pain not to be found, * A clinically underlying stenosis or discogenic problem not to be present. * Negative results from the following clinical examination tests; * Spurling test, * Lhermitte test, * Cervical distraction test, * Adson test, Exclusion Criteria: * Not meeting the inclusion criteria, * Positive neurological examination (positive motor presence, reflex or sensory abnormalities indicating spinal root compression) or abnormal neurological findings related to nerve compression in the upper limb * Systemic rheumatological or metabolic diseases or cancer * Refusal to participate in the study, * Failure to complete treatment, * Having any neurological problem * Severe psychological illnesses

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Conditions

The condition(s) this trial relates to.

chronic pain syndrome Neck Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic pain syndrome Neck pain Rehabilitation

Contacts and locations

Locations

  • Acibadem University

    Istanbul, Turkey, +90, Turkey (Türkiye)

  • Nuray ALACA

    Istanbul, Turkey, +90, Turkey (Türkiye)

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