Immune-Guided drug break could cut infections in transplant patients

NCT ID NCT06639854

First seen Nov 06, 2025 · Last updated May 15, 2026 · Updated 23 times

Summary

This study looks at whether measuring a patient's immune response to cytomegalovirus (CMV) can help decide when to stop the preventive drug letermovir after a stem cell transplant. About 105 transplant recipients at high risk for CMV will have their letermovir dosing adjusted based on immune system markers. The goal is to see if this personalized approach reduces post-treatment CMV infections better than the standard daily dosing schedule.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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