Supercharged poop pills aim to heal radiation gut damage
NCT ID NCT07331688
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a special bacterial strain (CMTS0515) to a standard fecal transplant can better relieve gut symptoms caused by radiation therapy for cancer. Sixty adults who completed radiation for abdominal or pelvic cancer will receive either the enhanced or standard transplant via a tube into the intestine. The main goal is to see if the enhanced version is at least as good as the standard at reducing radiation injury scores.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fecal microbiota transplant (enhanced with CMTS0515)
- What this could lead to
- If it works, this could offer a better way to manage chronic gut problems caused by radiation therapy, improving quality of life for cancer survivors.
- What could go wrong
- This is an early-phase trial with only 60 participants, so results may not apply to everyone. The treatment involves transplanting donor bacteria, which carries a small risk of infection or unexpected side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Microbiota Medicine & Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, 210011, China
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