Supercharged poop pills aim to heal radiation gut damage

NCT ID NCT07331688

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a special bacterial strain (CMTS0515) to a standard fecal transplant can better relieve gut symptoms caused by radiation therapy for cancer. Sixty adults who completed radiation for abdominal or pelvic cancer will receive either the enhanced or standard transplant via a tube into the intestine. The main goal is to see if the enhanced version is at least as good as the standard at reducing radiation injury scores.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fecal microbiota transplant (enhanced with CMTS0515)

What this could lead to

If it works, this could offer a better way to manage chronic gut problems caused by radiation therapy, improving quality of life for cancer survivors.

What could go wrong

This is an early-phase trial with only 60 participants, so results may not apply to everyone. The treatment involves transplanting donor bacteria, which carries a small risk of infection or unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

enteritis radiation proctitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Microbiota Medicine & Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University

    Nanjing, Jiangsu, 210011, China