Experimental CAR T-Cell therapy for leukemia shows early promise but study halted

NCT ID NCT05654779

First seen Feb 15, 2026 · Last updated May 12, 2026 · Updated 13 times

Summary

This early-phase study tested a new cell therapy (LCAR-AMDR cells) in 4 people with acute myeloid leukemia that had come back or not responded to standard treatments. The therapy uses specially engineered immune cells to target two proteins on leukemia cells. The study was terminated early, and its main goals were to check safety and find the right dose. Because lifelong medication may be needed, this is not a cure.

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Contacts and locations

Locations

  • Beijing Gobroad BoRen Hospital

    Beijing, Beijing Municipality, 100070, China

  • Chinese Academy of Medical Science and Blood Disease Hospital

    Tianjin, Tianjin Municipality, 300020, China

Conditions

Explore the condition pages connected to this study.