New drug combo challenges standard chemo for blood cancer
NCT ID NCT04285567
Summary
This completed Phase 3 trial compared a newer drug combination (venetoclax + obinutuzumab) against standard chemotherapy regimens for adults with previously untreated chronic lymphocytic leukemia (CLL). The goal was to see which approach was more effective at controlling the cancer and which was safer. The study focused on patients who were otherwise relatively fit and whose cancer did not have specific high-risk genetic features.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AO Santa Maria della Misericordia
Perugia, Umbria, 6132, Italy
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ASST Grande Ospedale Metropolitano Niguarda;Ematologia
Milan, Lombardy, 20162, Italy
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American Oncology Partners of Maryland, PA
Bethesda, Maryland, 20817, United States
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Azienda Ospedaliero Universitaria Maggiore della Carità;SCDU Ematologia
Novara, Piedmont, 28100, Italy
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Azienda Ospedaliero Universitaria;Ematologia
Modena, Emilia-Romagna, 41125, Italy
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COMPLEJO HOSPITALARIO DE NAVARRA;Servicio de Hematología
Pamplona, Navarre, 31008, Spain
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Canberra Hospital
Canberra, Australian Capital Territory, 2605, Australia
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Centre Hospitalier Régional Universitaire de Tours - Hôpital Bretonneau;Hématologie et Thérapie Cellulaire
Tours, Indre-et-Loire, 37032, France
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Centre Hospitalier Universitaire de Caen Normandie
Caen, 14000, France
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Centre Hospitalier Universitaire de Poitiers
Poitiers, 86021, France
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Centre Hospitalier Universitaire de Reims - Hôpital Robert Debré;Hématologie Clinique
Reims, 51092, France
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Centre Hospitalier de Pérpignan;hématologie
Perpignan, Languedoc-Roussillon, 66046, France
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Centre Hospitalier intercommunal de Toulon La Seyne sur Mer
Toulon, Provence-Alpes-Côte d'Azur Region, 83100, France
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Clinique Victor Hugo- CCS du Mans
Le Mans, 72000, France
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Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico;U.O.C Ematologia
Milan, Lombardy, 20122, Italy
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Fondazione Policlinico Universitario Agostino Gemelli
Rome, Lazio, 168, Italy
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HENRI MONDOR HOSPITAL;Centre d'investigation clinique
Créteil, Val-de-Marne, 94000, France
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Hopital Claude Huriez - CHU de Lille;service maladies appareil digestif
Lille, Nord, 59037, France
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Hopital Haut Leveque Chu de Bordeaux
Pessac, Aquitaine, 33600, France
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Hospital General Universitario Morales Meseguer;Hematologia y Oncologia médica
Murcia, 30008, Spain
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Hospital Germans Trias i Pujol
Badalona, Barcelona, 8916, Spain
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Hospital Universitari Vall d'Hebron;Hematology
Barcelona, 8035, Spain
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Hospital Universitario La Paz;Hematología
Madrid, 28015, Spain
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Hospital Universitario Virgen del Rocío;Unidad Onco-Hematología Pediátrica
Seville, 41009, Spain
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Hospital Universitario de Toledo
Toledo, 45007, Spain
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Instituto Tumori Giovanni Paolo II;ONCOLOGIA MEDICA
Bari, Apulia, 70124, Italy
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Liverpool Hospital
Liverpool, New South Wales, 2170, Australia
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Medical Center of Aurora
Aurora, Colorado, 80012, United States
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Monash Health;Haematology Research
Clayton, Victoria, 3168, Australia
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Northern Hospital;Oncology and/or Hematology
Melbourne, Victoria, 3076, Australia
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Oncology & Hematology Associates of Southwest Virginia, Inc._Goldschmidt
Roanoke, Virginia, 24014, United States
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Ospedale San Martino;U.O. Clinica Ematologica
Genoa, Liguria, 16132, Italy
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Ospedale Vito Fazzi;U.O. Ematologia IV Piano Polo Oncologico
Lecce, Apulia, 73100, Italy
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Peter MacCallum Cancer Centre;Clinical Haematology
Melbourne, Victoria, 3050, Australia
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Policlinico Umberto I
Rome, Lazio, 161, Italy
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Port Macquarie - Mid North Coast Cancer Institute
Port Macquarie, New South Wales, 2444, Australia
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Royal Hobart Hospital
Hobart, Tasmania, 7000, Australia
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Royal North Shore Hospital
St Leonards, New South Wales, 2065, Australia
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University of Tennessee Medical Center;Office of Clinical Trials
Knoxville, Tennessee, 37920, United States
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centre hospitalier lyon sud;Service Hématologie
Pierre-Bénite, Rhône, 69310, France
Conditions
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