Can a leukemia drug be paused? trial tests break from Long-Term treatment
NCT ID NCT04963946
Summary
This study is testing whether it's safe and effective to stop taking the drug acalabrutinib after 18 months for older adults with a type of blood cancer called chronic lymphocytic leukemia (CLL). The goal is to see if taking a break from the drug reduces long-term side effects and the risk of the cancer becoming resistant, while still controlling the disease. After the initial 18 months, some participants will continue the drug, while others will stop and only restart it if their cancer symptoms return.
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Contacts and locations
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Locations
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ARGENTEUIL - Centre hospitalier Victor Dupouy
Argenteuil, France
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BOBIGNY - Hôpital Avicenne
Bobigny, France
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Bordeaux Pessac
Pessac, 33604, France
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CENTRE HOSPITALIER SAINTJEAN - Hématologie Clinique
Perpignan, 66000, France
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CERGY-PONTOISE - Centre Hospitalier René Dubos
Pontoise, France
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CHR ORLEANS - Hématologie
Orléans, 44100, France
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CHU Estaing - Hématologie Clinique Adulte
Clermont-Ferrand, 63000, France
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CHU Grenoble - Hématologie
Grenoble, 388043, France
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CHU Nancy Brabois
Vandœuvre-lès-Nancy, 54500, France
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CHU Pontchaillou - Hématologie Clinique BMT-HC
Rennes, 35033, France
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Centre Henri Becquerel - Service Hématologie Clinique
Rouen, 76038, France
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Centre Hospitalier Lyon Sud
Pierre-Bénite, 69495, France
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Centre Hospitalier Regional Metz Thionville
Metz, 57085, France
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Centre Hospitalier du Mans
Le Mans, 72000, France
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Centre Léon Bérard - Hématologie
Lyon, 69373, France
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Ch Avignon
Avignon, 84000, France
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Ch Cote Basque
Bayonne, 64109, France
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Chu Angers
Angers, 49933, France
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Chu Reims
Reims, 51092, France
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Corbeil-Essonnes -
Corbeil-Essonnes, France
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Hopital E.Muller
Mulhouse, 68100, France
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Hopital Pitie Salpetriere Service Hematologie Clinique - Pavillon de L'Enfant Et Adolescent
Paris, 75651, France
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Hôpital Bretonneau - Hématologie et Thérapie Cellulaire
Tours, 37044, France
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Hôpital Privé Sévigné
Cesson-Sévigné, 35510, France
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Hôpital Saint Vincent de Paul
Lille, 59000, France
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Hôpital Saint-Eloi - Hématologie Clinique
Montpellier, 34295, France
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Hôpital de la Milétrie - Hématologie et Thérapie Cellulaire
Poitiers, 86021, France
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IUCT ONCOPOLE - Hématologie
Toulouse, 31059, France
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Institut Paoli-Calmettes - Hématologie Clinique
Marseille, 13273, France
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Institut de Cancérologie Lucien Neuwirth
Saint-Priest-en-Jarez, 42271, France
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VERSAILLES - Hôpital André Mignot
Versailles, France
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Vannes - Chba
Vannes, France
Conditions
Explore the condition pages connected to this study.