Heart pouch clipping device studied in 198 patients

NCT ID NCT06203054

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 26 times

Summary

This study looks at how well a device called Penditure™ works to close off a small pouch in the heart (the left atrial appendage) during other heart surgeries. The goal is to prevent blood clots that can cause strokes. About 198 adults having heart surgery will get the device, and doctors will check if the pouch stays closed after 3 months and if there are any serious problems within 30 days.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LEFT ATRIAL APPENDAGE EXCLUSION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Ascension St. Vincent Heart Center

    Carmel, Indiana, 46290, United States

  • Barnes Jewish Hospital

    St Louis, Missouri, 63110, United States

  • Corewell Health

    Grand Rapids, Michigan, 49503, United States

  • Emory Saint Joseph's Hospital

    Atlanta, Georgia, 30342, United States

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Lankenau Institute for Medical Research

    Wynnewood, Pennsylvania, 19096, United States

  • Mayo Clinic Saint Marys Campus

    Rochester, Minnesota, 55905, United States

  • Northwestern Memorial Hospital

    Chicago, Illinois, 60611, United States

  • ProMedica Toledo Hospital

    Toledo, Ohio, 43606, United States

  • Saint Joseph's Hospital Health Center

    Syracuse, New York, 13203, United States

  • Swedish Medical Center Cherry Hill

    Seattle, Washington, 98112, United States

  • UPMC Pinnacle Harrisburg Campus

    Harrisburg, Pennsylvania, 17101, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of Michigan Health System

    Ann Arbor, Michigan, 48109, United States

  • University of Pittsburgh Medical Center UPMC Presbyterian

    Pittsburgh, Pennsylvania, 15213, United States

Conditions

Explore the condition pages connected to this study.