New drug CLIO-8221 enters human testing for advanced cancers
NCT ID NCT07300943
First seen Jan 05, 2026 · Last updated May 25, 2026 · Updated 21 times
Summary
This study tests a new drug, CLIO-8221, in about 306 adults whose solid tumors have spread or cannot be removed and who have already tried other treatments. The first part finds a safe dose; the second part checks if the drug shrinks tumors. The goal is to control the disease, not cure it.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AlfredHealth
RECRUITINGHeidelberg, Victoria, 3084, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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DFCI
NOT_YET_RECRUITINGBoston, Massachusetts, 02215-5450, United States
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Integrated Clinical Oncology Network Pty Ltd
RECRUITINGSouth Brisbane, Queensland, 4101, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Linear Clinical Research Ltd
RECRUITINGNedlands, Western Australia, 6009, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Peter Maccallum Cancer Centre
RECRUITINGBox Hill, Victoria, 3128, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Royal Melbourne Hospital
RECRUITINGMelbourne, Victoria, 3052, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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START Mountain
RECRUITINGWest Valley City, Utah, 84119, United States
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START San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
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Sarah Cannon Research Institute 335 24th Avenue North, Suite 400
RECRUITINGNashville, Tennessee, 37203, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
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Scientia Clinical Research
RECRUITINGRandwick, New South Wales, 2031, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.