New drug combo shows promise for blood cancers in early trial

NCT ID NCT06484062

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 23 times

Summary

This early-stage study is testing a new drug called cirtuvivint, alone or with another drug (ASTX727), in people with blood cancers MDS and AML. The goal is to find the safest dose and see how well it works. About 54 adults whose cancer has returned or not responded to treatment will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact Phone: •••-•••-••••

  • Emory University Hospital/Winship Cancer Institute

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Basking Ridge

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

    Contact

  • Memorial Sloan Kettering Bergen

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

    Contact

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

    Contact

  • Memorial Sloan Kettering Commack

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

    Contact

  • Memorial Sloan Kettering Monmouth

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

    Contact

  • Memorial Sloan Kettering Nassau

    RECRUITING

    Uniondale, New York, 11553, United States

    Contact Phone: •••-•••-••••

    Contact

  • Memorial Sloan Kettering Westchester

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••

    Contact

  • Rutgers Cancer Institute of New Jersey

    RECRUITING

    New Brunswick, New Jersey, 08903, United States

    Contact

    Contact Phone: •••-•••-••••

  • Siteman Cancer Center at Christian Hospital

    RECRUITING

    St Louis, Missouri, 63136, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Siteman Cancer Center at Saint Peters Hospital

    RECRUITING

    City of Saint Peters, Missouri, 63376, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Siteman Cancer Center at West County Hospital

    RECRUITING

    Creve Coeur, Missouri, 63141, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Siteman Cancer Center-South County

    RECRUITING

    St Louis, Missouri, 63129, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UC Comprehensive Cancer Center at Silver Cross

    SUSPENDED

    New Lenox, Illinois, 60451, United States

  • UChicago Medicine Northwest Indiana

    SUSPENDED

    Crown Point, Indiana, 46307, United States

  • University of Chicago Comprehensive Cancer Center

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Chicago Medicine-Orland Park

    SUSPENDED

    Orland Park, Illinois, 60462, United States

  • University of Maryland/Greenebaum Cancer Center

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-••••

    Contact

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06520, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.