Thousands tracked in Largest-Ever liver cancer bead therapy registry

NCT ID NCT02305459

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This registry followed over 1,000 liver cancer patients who received SIR-Spheres—tiny radioactive beads injected into the liver's blood supply to kill tumors. The goal was to see how this treatment is used in real hospitals and how it affects survival, side effects, and quality of life. No new treatment was tested; instead, researchers collected data from routine care to better understand the therapy's impact.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Yttrium-90 loaded SIR-Spheres microspheres (radioactive beads delivered via catheter to liver tumors)

What this could lead to

If successful, this registry could confirm how well SIR-Spheres works in everyday practice, potentially guiding better use of this therapy for liver cancer patients.

What could go wrong

This is an observational registry, not a controlled trial, so it cannot prove cause and effect. Results may vary widely across patients and hospitals.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

carcinoma of liver and intrahepatic biliary tract hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cardiovascular and Interventional Radiological Society of Europe

    Vienna, 1010, Austria