New shot aims to stop painful hives where standard meds fail

NCT ID NCT05405660

Summary

This study tested an injectable drug called barzolvolimab (CDX-0159) for adults with chronic hives triggered by cold or skin friction. The goal was to see if it could better control symptoms in people whose hives weren't fully managed by standard antihistamine pills. Researchers compared three groups over 20 weeks: two different doses of the drug and a placebo, to measure effectiveness and safety.

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Contacts and locations

Locations

  • "LOR" Clinic

    Riga, LV-1004, Latvia

  • "Medical Center Ekselsior" OOD

    Sofia, Bulgaria

  • "University Multiprofile Hospital for Active Treatment 'Aleksandrovska" EAD, Clinic of Clinical Allergology

    Sofia, Bulgaria

  • Allergo-Derm Bakos Kft

    Szolnok, 5000, Hungary

  • Allergy & Asthma Consultants

    Redwood City, California, 94063, United States

  • Allergy & Asthma Specialists, PSC

    Owensboro, Kentucky, 42301, United States

  • Allergy Associates of Utah

    Murray, Utah, 84107, United States

  • Allergy Partners of Kerrville

    Kerrville, Texas, 78028, United States

  • Allervie Clinical Research

    Montgomery, Alabama, 36106, United States

  • Balvi and Gulbene Hospital Union

    Balvi, LV-4501, Latvia

  • Center of Allergy Diagnosis and Treatment

    Vilnius, LT-09109, Lithuania

  • Center of Allergy and Immunology

    Tbilisi, 0159, Georgia

  • Centrum Medyczne PLEJADY

    Krakow, 30-363, Poland

  • Children Clinical University Hospital

    Riga, LV-1004, Latvia

  • Clinical Research Center of Alabama

    Birmingham, Alabama, 35249, United States

  • Consilium Medicum

    Riga, LV-1010, Latvia

  • Dawes Fretzin Dermatology Group, LLC

    Indianapolis, Indiana, 46250, United States

  • Debreceni Egyetem Klinikai Központ (DEKK), Bőrgyógyászati Klinika

    Debrecen, H-4032, Hungary

  • Dr PJ Sebastian

    Durban, KwaZulu-Natal, 4092, South Africa

  • East Tallin Central Hospital

    Tallinn, 11312, Estonia

  • Elbe Klinikum Buxtehude

    Buxtehude, Lower Saxony, 21614, Germany

  • FCRN Clinical Trial Centre Vaal Triangle

    Vereeniging, Gauteng, 1935, South Africa

  • HGU de Alicante

    Alicante, 03010, Spain

  • Hannover Medical University

    Hanover, Lower Saxony, 30625, Germany

  • Healthy Future

    Tbilisi, 0119, Georgia

  • High Technology Hospital Medcenter

    Batumi, 6000, Georgia

  • Hospital Arnau de Vilanova

    Valencia, 46015, Spain

  • Hospital Bellvitge

    Barcelona, 8907, Spain

  • Hospital Regional Universitario de Málaga

    Málaga, 29009, Spain

  • Hospital Vall d´ Hebron

    Barcelona, 9035, Spain

  • IMMUNOe Research Centers

    Centennial, Colorado, 80112, United States

  • Iatros International

    Bloemfontein, Free State, 9324, South Africa

  • Institute for Asthma and Allergy, PC/Department of Clinical Research

    Chevy Chase, Maryland, 20815, United States

  • Institute of Allergology IFA

    Berlin, 12203, Germany

  • JSC Ausros Medicinos Centras

    Kaunas, 49387, Lithuania

  • JSC Inlita

    Vilnius, 08406, Lithuania

  • Kern Research, Inc

    Bakersfield, California, 93301, United States

  • Klinika Ambroziak sp. z o.o.

    Warsaw, 02-953, Poland

  • Klinikum Oldenburg gGmbH - Klinik f. Dermatologie u. Allergologie

    Oldenburg, Lower Saxony, 26133, Germany

  • LMU Klinikum - Klinik und Poliklinik für Dermatologie und Allergologie DASZ-Dermato-Allergologisches Studien Zentrum

    München, Bavaria, 80337, Germany

  • Little Rock Allergy & Asthma CRC

    Little Rock, Arkansas, 72205, United States

  • Luxderm Specjalistyczny Gabinet Dermatologiczny Prof. Doroty Krasowskiej

    Lublin, 20-573, Poland

  • Malopolskie Centrum Alergologii

    Krakow, 31-624, Poland

  • Medical Center "SYNEXUS SOFIA", EOOD

    Sofia, Bulgaria

  • Medical Center Iskar- EOOD Office of Clinical Allergology

    Sofia, 1504, Bulgaria

  • Medicome Sp. z o.o.

    Oświęcim, 32600, Poland

  • Medicover Integrated Clinical Services Sp. zo.o.

    Torun, 87-100, Poland

  • Multiprofile Clinic Consilium Medulla

    Tbilisi, 0186, Georgia

  • Newtown Clinical Research

    Johannesburg, Gauteng, 2113, South Africa

  • One of a Kind Clinical Research Center, LLC

    Paradise Valley, Arizona, 85253, United States

  • Outpatient Clinic for Individual Practice for Specialized Outpatient

    Razgrad, 7200, Bulgaria

  • Pauls Stradins Clinical University Hospital

    Riga, LV-1002, Latvia

  • Respiratory Medicine Research Institute of Michigan, PLC

    Ypsilanti, Michigan, 48197, United States

  • Sarasota Clinical Research

    Sarasota, Florida, 34239, United States

  • Semmelweis Egyetem, ÁOK, Bőr-, Nemikórtani és Bőronkológiai Klinika

    Budapest, 1085, Hungary

  • Semmelweis Egyetem, ÁOK, Bőr-, Nemikórtani és Bőronkológiai Klinika

    Budapest, Hungary

  • Synapta Clinical Research

    Durban, KwaZulu-Natal, 4001, South Africa

  • The University of Cape Town - Lung Institute

    Cape Town, Mowbray, 7700, South Africa

  • Treasure Valley Medical Research

    Boise, Idaho, 83706, United States

  • Ubuntu Clinical Research

    Lenasia, Gauteng, 1827, South Africa

  • Universidad de Navarra

    Madrid, 28027, Spain

  • Universitaetsklinikum Giessen u. Marburg GmbH

    Marburg, Hesse, 35043, Germany

  • University Multiprofile Hospital for Active Treatment "Prof. Dr. Stoyan Kirkovich" AD

    Stara Zagora, Bulgaria

  • University of Cincinnati

    Cincinnati, Ohio, 45267, United States

  • Universitätsklinikum Augsburg

    Augsburg, Bavaria, 86179, Germany

  • Universitätsklinikum Dresden

    Dresden, Saxony, 01307, Germany

  • Universitätsklinikum Düsseldorf - Dermatologie

    Düsseldorf, North Rhine-Westphalia, 40225, Germany

  • Universitätsklinikum Essen Klinikum f. Dermatologie, Venerologie u. Allergologie Hufelandstr

    Essen, North Rhine-Westphalia, 45122, Germany

  • Universitätsklinikum Heidelberg - Dermatologie

    Heidelberg, 69120, Germany

  • Universitätsklinikum Münster Klinik u. Poliklinik f. Dermatologie

    Münster, North Rhine-Westphalia, 48149, Germany

  • Universitätsklinikum Schleswig-Holstein - Zentrum für entzündliche Hauterkrankungen

    Kiel, Schleswig-Holstein, 24105, Germany

  • Uniwersytecki Szpital Kliniczny nr 1 w Lodzi

    Lodz, 90-153, Poland

  • Uniwersytecki Szpital Kliniczny w Opolu, Pododdział Chorób Wewnętrznych i Alergologii

    Opole, 45-401, Poland

  • Vahlberg & Pild Clinic

    Tallinn, 10134, Estonia

  • WorthWhile Clinical Trials

    Benoni, Gauteng, 1500, South Africa

  • Óbudai Egészségügyi Centrum

    Zalaegerszeg, 8900, Hungary

Conditions

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