New drug trial aims to tame relapsing childhood kidney disease

NCT ID NCT05627557

Summary

This study is testing if a drug called obinutuzumab works better than the standard drug MMF to keep a childhood kidney disease from coming back. It involves 85 children and young adults (ages 2-25) who have a form of the disease that frequently relapses. The main goal is to see which treatment keeps patients in remission and off steroids for a full year.

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Contacts and locations

Locations

  • Children's Healthcare of Atlanta Center for Advanced Pediatrics

    Atlanta, Georgia, 30329-2309, United States

  • Chu Toulouse

    Toulouse, Haute-Garonne, 31300, France

  • Dokkyo Medical University Hospital

    Shimotsuga-Gun, 321-0293, Japan

  • Dzieciecy Szpital Kliniczny UCK WUM

    Warsaw, 02-091, Poland

  • Fundacao Faculdade Regional de Medicina de Sao Jose Do Rio Preto Hospital de Base - PPDS

    São José do Rio Preto, São Paulo, 15090-000, Brazil

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601-1915, United States

  • Henan Children's Hospital Zhengzhou Children's Hospital

    Zhengzhou, 450018, China

  • Hokkaido University Hospital

    Hokkaido, 060-8648, Japan

  • Hopital Femme Mere Enfants

    Bron, 69500, France

  • Hopital Henri Mondor

    Créteil, 94010, France

  • Hopital Robert Debre

    Paris, 75935, France

  • Hospital Sant Joan de Deu - PIN

    Espluges de Llobregat, Barcelona, 08950, Spain

  • Hospital Universitario Cruces

    Barakaldo, Vizcaya, 48903, Spain

  • Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo

    São Paulo, São Paulo, 05403-000, Brazil

  • Hyogo prefectural Kobe Children's Hospital

    Hyogoken, 6500047, Japan

  • Irmandade Da Santa Casa de Misericordia de Porto Alegre

    Porto Alegre, Rio Grande do Sul, 90020-090, Brazil

  • Istituto G Gaslini Ospedale Pediatrico IRCCS - INCIPIT - PIN

    Genoa, Liguria, 16147, Italy

  • Kitasato University Hospital

    Sagamihara-Shi, 252-0329, Japan

  • Kobe University Hospital

    Kobe, 650-0017, Japan

  • Levine Children's Hospital

    Charlotte, North Carolina, 28203-5866, United States

  • Lucile Packard Children's Hospital - Stanford

    Palo Alto, California, 94304-1601, United States

  • Memorial Healthcare System

    Hollywood, Florida, 33021, United States

  • National Center for Child Health and Development

    Tokyo, 157-8535, Japan

  • Nemours Children's Hospital

    Orlando, Florida, 32827-7884, United States

  • Nicklaus Children's Hospital

    Miami, Florida, 33155-3009, United States

  • Ospedale Infantile Regina Margherita - INCIPIT - PIN

    Turin, Piedmont, 10126, Italy

  • Peking University First Hospital

    Beijing, 102627, China

  • Shiga University Of Medical Science Hospital

    Ōtsu, 520-2192, Japan

  • The First Affiliated Hospital of Sun Yat-sen University

    Guangzhou, 510080, China

  • The children's hospital , Zhejiang university school of medicine

    Hangzhou, 310003, China

  • Tokyo Metropolitan Children's Medical Center

    Fuchu-Shi, 183-0042, Japan

  • Tongji Hospital Tongji Medical College Huazhong University of Science and Technology

    Wuhan, 430040, China

  • UZ Gent

    Ghent, 9000, Belgium

  • University of South Florida

    Tampa, Florida, 33606-3475, United States

  • University of Utah - Primary Children's Hospital - PPDS

    Salt Lake City, Utah, 84113-1103, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22903, United States

  • Uniwersyteckie Centrum Kliniczne

    Gdansk, Poland

  • Xi'an Children's Hospital

    Xi'an, 710003, China

  • Yokohama City University Medical Center

    Yokohama, 232-0024, Japan

Conditions

Explore the condition pages connected to this study.