New hope for kids needing transplants: gentler prep drugs tested

NCT ID NCT02349906

Summary

This study aimed to find a safer and effective drug treatment for children needing a stem cell transplant for serious non-cancerous diseases like immune deficiencies and metabolic disorders. It directly compared two different drug combinations used to prepare a child's body to receive the transplant. The goal was to see if one regimen was better at reducing serious complications and deaths related to the transplant procedure itself.

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Contacts and locations

Locations

  • Department of Pediatric Oncology & Hematology, Charite Berlin

    Berlin, 13353, Germany

  • Dzieciecy Szpital Kliniczny im. A. Gebali w Lublinie

    Lublin, 20-093, Poland

  • Hannover Medical University, Dep. of Paediatrics, Paediatric Haematology and Oncology

    Hanover, Germany

  • Heidelberg University Hospital

    Heidelberg, 69120, Germany

  • Oncoematologia Pediatrica A.O. di Perugia Ospedale S. Maria della Misericordia

    Perugia, 06156, Italy

  • Ospedale Bambino Gesu Roma

    Rome, 00165, Italy

  • Ospedale Infantile Regina Margherita Torino

    Turin, 10126, Italy

  • Reparto Trapianti Midollo Osseo Clinica Pediatrica Universitaria Fondazione MBBM-Ospedale San Gerardo

    Monza, 20900, Italy

  • S.C. Oncoematologia Pediatrica Fondazione IRCCS Policlinico San Matteo

    Pavia, 27100, Italy

  • SC Oncoematologia Pediatrica Ospedale Pediatrico Microcitemico "Antonio Cao" A.O. Brotzu

    Cagliari, 09121, Italy

  • Szpital Uniwersytecki im. dr Antoniego Jurasza

    Bydgoszcz, 85-094, Poland

  • U.O. Oncoematologia Pediatrica Azienda Ospedaliero Universitaria Pisana Ospedale S. Chiara

    Pisa, 56100, Italy

  • U.O.C. Oncoematologia Pediatrica Policlinico "G.B. Rossi" - AOUI Verona

    Verona, 37134, Italy

  • UOC Ematologia ed Oncologia Pediatrica con TMO AOU Policlinico Vittorio Emanuele

    Catania, 95123, Italy

  • Ulm, University Hospital, Clinic for Children and Adolescents

    Ulm, 89075, Germany

  • University Children's Hospital Essen Pediatric stem cell transplantation

    Essen, 45122, Germany

  • University Hospital Frankfurt

    Frankfurt am Main, 60590, Germany

  • University Hospital Motol, Dep. of Paediatric Haematology and Oncology

    Prague, Czechia

  • University of Jena, Department of Pediatrics

    Jena, 07747, Germany

  • Uniwersytecki Szpital Dzieciecy w Krakowie

    Krakow, 30-663, Poland

  • Wroclaw Medical University, Department of Pediatric Hematology/Oncology and BMT

    Wroclaw, 50-368, Poland

Conditions

Explore the condition pages connected to this study.