New combo aims to boost CAR-T success in tough lymphoma

NCT ID NCT07489989

First seen Mar 25, 2026 · Last updated May 13, 2026 · Updated 5 times

Summary

This study tests whether adding two drugs—chidamide and a PD-1 inhibitor—after CAR-T cell therapy can help people with relapsed or hard-to-treat B-cell lymphoma stay cancer-free longer. About 30 adults with aggressive lymphoma that has come back or not responded to treatment will receive this combination as maintenance therapy. The goal is to reduce relapse rates and improve survival by overcoming resistance and boosting the immune system's attack on cancer cells.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chinese PLA General Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100853, China

Conditions

Explore the condition pages connected to this study.