New hope for rare sinus cancer: combined therapy shows promise

NCT ID NCT07449949

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a treatment plan for adults with a rare cancer of the nasal and sinus cavities called rhabdomyosarcoma. The plan involves chemotherapy and radiation before and after surgery. The goal is to see if this approach can shrink tumors and improve survival. The study will enroll 43 people who have not been treated before.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Vincristine, Actinomycin D, Epirubicin, Cisplatin, Cyclophosphamide, and radiation therapy
What this could lead to
If successful, this could provide a standard treatment approach for a rare cancer that currently lacks established guidelines.
What could go wrong
This is a small, single-arm study with only 43 participants, so results may not apply to all patients. The treatment involves strong chemotherapy and radiation, which can cause significant side effects.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • EENT hospital of Fudan University

    Shanghai, China, 200000, China

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