New cream promises firmer, hydrated skin for aging adults

NCT ID NCT07398989

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a topical skincare product, Cetaphil Hydrating and Firming Cream, on 32 adults aged 40-60 with mild-to-moderate crepey skin. Participants applied the cream twice daily to knees, thighs, and hands for 12 weeks. Researchers measured changes in skin hydration, firmness, and texture using clinical grading and devices like a Corneometer. The goal was to see if the cream could improve skin condition without irritation.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Cetaphil Hydrating and Firming Cream Skin Activator
What this could lead to
If it works, this could provide a simple, over-the-counter option to improve skin hydration and firmness in aging skin.
What could go wrong
This is a small, completed Phase 4 trial with only 32 participants, so results may not apply to everyone. The product is a cosmetic cream, not a medical treatment for serious skin conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ablon Skin Institute & Research Center

    Manhattan Beach, California, 90266, United States

  • Clinical Research Center of the Carolinas

    Charleston, South Carolina, 29407, United States

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