New cream promises firmer, hydrated skin for aging adults
NCT ID NCT07398989
First seen Feb 14, 2026 · Last updated Jun 23, 2026 · Updated 13 times
Summary
This study tested a topical skincare product, Cetaphil Hydrating and Firming Cream, on 32 adults aged 40-60 with mild-to-moderate crepey skin. Participants applied the cream twice daily to knees, thighs, and hands for 12 weeks. Researchers measured changes in skin hydration, firmness, and texture using clinical grading and devices like a Corneometer. The goal was to see if the cream could improve skin condition without irritation.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ablon Skin Institute & Research Center
Manhattan Beach, California, 90266, United States
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Clinical Research Center of the Carolinas
Charleston, South Carolina, 29407, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cetaphil Hydrating and Firming Cream Skin Activator
What this could lead to
If it works, this could provide a simple, over-the-counter option to improve skin hydration and firmness in aging skin.
What could go wrong
This is a small, completed Phase 4 trial with only 32 participants, so results may not apply to everyone. The product is a cosmetic cream, not a medical treatment for serious skin conditions.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.