Radioactive implants during surgery aim to stop head and neck Cancer's return

NCT ID NCT02467738

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study tested whether placing tiny radioactive seeds (Cesium-131) into the wound during surgery can kill leftover cancer cells in patients whose head and neck cancer has come back. Thirty adults with resectable tumors received the implant right after tumor removal. Researchers tracked how long patients stayed cancer-free and monitored side effects like infection or poor healing. The goal is to see if this extra step can lower the chance of cancer returning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cesium-131 (radioactive implant)

What this could lead to

If successful, this approach could offer a new way to reduce cancer recurrence after surgery for head and neck cancer that has come back.

What could go wrong

This is a very early pilot study with only 30 participants, so results may not apply broadly. Risks include infection, poor wound healing, bleeding, and fistula formation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck cancer head and neck carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sidney Kimmel Cancer Center at Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States