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New hope for advanced cervical cancer: immunotherapy combo tested

NCT ID NCT03556839

Completed Disease control Sponsor: Grupo Español de Investigación en Cáncer de Ovario Source: ClinicalTrials.gov ↗

First seen Apr 21, 2026 · Last updated Apr 30, 2026 · Updated 2 times

Summary

This study tested whether adding the immunotherapy drug atezolizumab to standard chemotherapy and bevacizumab helps people with advanced, persistent, or recurrent cervical cancer live longer. About 410 participants received either the standard treatment or the standard plus atezolizumab. The goal was to see if the new combination improves survival and tumor shrinkage.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AOU Città della Salute e della Scienza di Torino, Presidio Sant'Anna

    Torino, Italy

  • ASST Lecco

    Lecco, Italy

  • AUSL Romagna - P.O. di Ravenna, Lugo, Faenza, Rimini e Cattolica

    Ravenna, Italy

  • Azienda Ospedaliero Universitaria Pisana

    Pisa, Italy

  • Azienda Ospedaliero-Universitaria Di Ferrara

    Ferrara, Italy

  • Azienda Sanitaria Universitaria Integrata Di Udine

    Udine, Italy

  • Azienda Usl - Irccs Di Reggio Emilia

    Reggio Emilia, Italy

  • CHU Jean Minjoz

    Besançon, France

  • Cancer Institute Hospital

    Kōtoku, Japan

  • Centre Antoine Lacassagne

    Nice, France

  • Centre CARIO-HPCA

    Plérin, France

  • Centre François Baclesse

    Caen, France

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, France

  • Centre Léon Bérard

    Lyon, France

  • Centre Oscar Lambret

    Lille, 59000, France

  • Complejo Hospitalario Regional de Málaga

    Málaga, Málaga, 29010, Spain

  • Fondazione Del Piemonte Per L'Oncologia

    Candiolo, Italy

  • Groupe Hospitalier Diaconesses-Croix Saint-Simon

    Paris, France

  • Gustave Roussy

    Villejuif, France

  • H. Clínic Barcelona

    Barcelona, Barcelona, 08036, Spain

  • HEGP

    Paris, France

  • Haukeland University Hospital

    Bergen, Norway

  • Helios-Klinikum Wuppertal

    Wuppertal, 42283, Germany

  • Hokkaido Cancer Center

    Hokkaido, Japan

  • Hospital Clinico Universitario Virgen Arrixaca

    Murcia, Murcia, 30120, Spain

  • Hospital Clínico Universitario de Valencia

    Valencia, Valencia, 46010, Spain

  • Hospital Miguel Servet

    Zaragoza, Zaragoza, 50009, Spain

  • Hospital Quirón de Valencia

    Valencia, 46010, Spain

  • Hospital Ramon y Cajal

    Madrid, Madrid, 28034, Spain

  • Hospital Reina Sofía Cordoba

    Córdoba, Cordoba, 14004, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, Madrid, 28041, Spain

  • Hospital Universitario Donostia- Donostia Unibertsitate Ospitalea

    Donostia / San Sebastian, Gipuzkoa, 20014, Spain

  • Hospital Universitario La Paz

    Madrid, Madrid, 28046, Spain

  • Hospital Universitario Son Espases

    Palma de Mallorca, Balearic Islands, 07120, Spain

  • Hospital Virgen de la Salud

    Toledo, 45004, Spain

  • Hospital de la Vall d'Hebron

    Barcelona, Barcelona, 08035, Spain

  • Hosptial Clinico Universitario de Santiago de Compostela

    Santiago de Compostela, Santiago de Compostela, 15706, Spain

  • Hyogo Cancer Center

    Hyōgo, Japan

  • Hôpital Privé du Confluent S.A.S.

    Nantes, France

  • Hôpitaux Universitaires

    Strasbourg, France

  • ICM Val d'Aurelle

    Montpellier, France

  • ICO Centre René Gauducheau

    Saint-Herblain, France

  • ICO Girona

    Girona, Girona, 17007, Spain

  • ICO Paul Papin

    Angers, 49055, France

  • Institut Bergonié

    Bordeaux, France

  • Institut Claudius Régaud

    Toulouse, France

  • Instituto Valenciano de Oncología

    Valencia, Valencia, 46009, Spain

  • Intitut Català d' Oncolgia L' Hospitalet

    L'Hospitalet de Llobregat, Barcelona, 08907, Spain

  • Irccs S. Raffaele - Milano

    Milan, Italy

  • Irst Irccs

    Meldola FC, Italy

  • Istituto Europeo di Oncologia

    Milan, Italy

  • Istituto Nazionale Tumori Di Napoli Irccs Pascale

    Naples, Italy

  • Istituto Oncologico Veneto (IOV) IRCCS

    Padova, Italy

  • Karolinska University Hospital

    Stockholm, Sweden

  • Keio University Hospital

    Tokyo, Japan

  • Kurume University Hospital

    Fukuoka, Japan

  • Lindköping University Hospital

    Linköping, Sweden

  • Massey Cancer Center

    Richmond, Virginia, 980037, United States

  • Niigata University Medical & Dental Hospital

    Niigata, Japan

  • Oslo University Hospital

    Oslo, Norway

  • Ospedale Lecce 'Vito Fazzi'

    Lecce, Italy

  • Ospedale Ordine Mauriziano

    Torino, Italy

  • Ospedale San Gerardo

    Monza, Italy

  • Parc Taulí

    Sabadell, Barcelona, 08208, Spain

  • Policlinico Universitario A. Gemelli

    Roma, Italy

  • Saitama medical university international medical center

    Hidaka, Japan

  • Shizuoka Cancer Center

    Shizuoka, Japan

  • Skane University Hospital

    Lund, Sweden

  • University Hospital of North Norway

    Tromsø, Norway

  • Universitätsmedizin Mainz

    Mainz, 55131, Germany

  • Uppsala University Hospital

    Uppsala, Sweden

  • Willis Knighton Cancer Center

    Shreveport, Louisiana, 71103, United States

Conditions

Explore the condition pages connected to this study.

CARCINOMA OF THE CERVIX, STAGE IVB