New radiation technique aims to spare cervical cancer patients from gut woes

NCT ID NCT05197881

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This trial tests a new type of radiation therapy for cervical cancer that adjusts the beam daily based on the patient's anatomy. The goal is to reduce acute bowel side effects like diarrhea and urgency. About 125 patients with advanced cervical cancer will receive this treatment, and their reported side effects will be compared to historical rates from standard radiation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Daily adaptive external beam radiation therapy delivered via Varian Ethos system

What this could lead to

If successful, this approach could reduce acute gastrointestinal side effects like diarrhea and urgency during radiation for cervical cancer, making treatment more tolerable.

What could go wrong

This is an early-phase, single-arm study comparing results to historical data, not a randomized trial. The new technique may not significantly reduce side effects or could have unforeseen issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cervical cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Fox Chase Cancer Center

    RECRUITING

    Philadelphia, Pennsylvania, 19111, United States

    Contact Email: •••••@•••••

  • Moores Cancer Center at UC San Diego Health

    RECRUITING

    La Jolla, California, 92037, United States

    Contact Email: •••••@•••••

  • University of Alabama Birmingham

    RECRUITING

    Burmingham, Alabama, 35233, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • University of Arkansas Medical Sciences

    RECRUITING

    Little Rock, Arkansas, 72205, United States

    Contact Email: •••••@•••••

  • University of Texas Southwestern

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••