Could a cement injection stop spine fractures after cancer radiation?

NCT ID NCT02387905

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 31 times

Summary

This study tests whether injecting bone cement into the spine can prevent fractures in cancer patients whose tumors have spread to the spine and who are receiving high-dose radiation. About 87 adults with solid tumors and spine metastases will either get standard radiation alone or radiation plus the cement procedure. The main goal is to see if the cement lowers the rate of spine fractures within three months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bone cement (vertebral body cement augmentation)

What this could lead to

If it works, this procedure could prevent painful spine fractures in cancer patients after radiation, reducing pain and improving quality of life.

What could go wrong

This is a mid-stage trial with only 87 participants, so results may not apply to everyone. The procedure itself carries risks like cement leakage or infection.

Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm in the spinal cord Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.