Promising combo for resistant prostate cancer falls short

NCT ID NCT04179864

First seen Apr 08, 2026 · Last updated May 12, 2026 · Updated 6 times

Summary

This study tested a new drug, tazemetostat, combined with standard hormone therapies (enzalutamide or abiraterone/prednisone) in men with advanced prostate cancer that no longer responds to hormone treatment. The goal was to see if the combination was safe and could delay cancer growth. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Academisch Ziekenhuis Groeninge Campus Kennedylaan

    Kortrijk, West Vlaanderen, Belgium

  • Associated Medical Professionals of NY, PLLC - Urology

    Syracuse, New York, 13210, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Clinica Universidad de Navarra

    Pamplona, Spain

  • Comprehensive Cancer Centers of Nevada - Central Valley

    Las Vegas, Nevada, 89169, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Genesis Healthcare Partners

    San Diego, California, 92123, United States

  • Hematology Oncology Associates of the Treasure Coast

    Port Saint Lucie, Florida, 34952, United States

  • Hospital Clinico San Carlos

    Madrid, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, Spain

  • Hospital Universitario La Paz

    Madrid, Spain

  • Hospital Universitario de Jerez de la Frontera

    Jerez de la Frontera, Cadiz, Spain

  • Hospital de la Santa Creu i. Sant Pau

    Barcelona, Spain

  • Hospital del Mar Parc de Salut Mar

    Barcelona, Spain

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Montefiore Einstein Center for Cancer Care

    The Bronx, New York, 10461, United States

  • SCRI - Tennessee Oncology Chattanooga

    Chattanooga, Tennessee, 37404, United States

  • SCRI - Tennessee Oncology Nashville

    Nashville, Tennessee, 37203, United States

  • The Urology Center Of Colorado

    Denver, Colorado, 80211, United States

  • University of Pittsburgh Medical Center - Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

  • Urology Associates P.C.

    Hendersonville, Tennessee, 37075, United States

  • Urology San Antonio

    San Antonio, Texas, 78229, United States

  • XCancer - Northwest Oncology and Hematology

    Rolling Meadows, Illinois, 60008, United States

  • XCancer - Tennesee Cancer Specialists

    Knoxville, Tennessee, 37909, United States

Conditions

Explore the condition pages connected to this study.