Engineered immune cells target cause of painful blistering disease

NCT ID NCT04422912

Summary

This study is testing two new cell therapies for adults with active pemphigus vulgaris, a painful autoimmune disease that causes severe blisters. Researchers are giving patients their own immune cells that have been specially engineered in a lab to target and potentially control the disease. The main goals are to find safe doses and see if these treatments can lead to lasting remission for people who haven't responded well to standard treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Columbia University

    RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • MD Anderson Texas Medical Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mount Sinai - Icahn School of Medicine

    WITHDRAWN

    New York, New York, 10029, United States

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford University, Dept. of Dermatology

    RECRUITING

    Redwood City, California, 94063, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UC Davis, Dept. of Dermatology

    RECRUITING

    Sacramento, California, 95816, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UT Southwestern Medical Center, Dept. of Dermatology

    RECRUITING

    Dallas, Texas, 75235, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of North Carolina, Department of Dermatology

    WITHDRAWN

    Chapel Hill, North Carolina, 27516, United States

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Washington

    COMPLETED

    Seattle, Washington, 98109, United States

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06520, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.