What do you risk for a chance at remission? cell therapy survey asks
NCT ID NCT07813000
First seen Sep 10, 2026 · Last updated Sep 11, 2026 · Updated 1 time
Summary
Cell therapies such as CAR-T and TIL therapy are emerging options for advanced solid tumors, but their benefits are uncertain and side effects can be severe. Researchers at Zhejiang University are surveying about 420 cancer doctors and 600 patients in China to learn how each group weighs efficacy, safety, treatment burden, and cost. Participants answer a one-time online questionnaire with hypothetical treatment choices, and the study compares the two groups' priorities. The goal is to inform shared decision-making and how cell therapies are developed and assessed.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If the study maps what doctors and patients value, it could help shape shared decision-making, trial design, and how regulators weigh cell therapy risks against benefits.
- What could go wrong
- This is a survey of hypothetical choices, not real treatments, so what people say they prefer may not match what they decide in a clinic. The findings will reflect views in China and may not apply elsewhere.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,020 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Approximately 420 licensed oncology physicians and 600 adult patients with advanced solid tumors will be enrolled in China.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Physicians Physicians must meet ALL of the following criteria: 1. Hold a valid medical practitioner license issued in the People's Republic of China and currently practice at a medical institution in China; 2. Specialize in medical oncology or another specialty directly involved in the diagnosis and treatment of solid tumors (e.g., thoracic oncology, gastrointestinal oncology, genitourinary oncology, or gynecologic oncology; surgical oncologists or radiation oncologists with prescribing authority for systemic anticancer therapy are also eligible); 3. Hold a professional title of attending physician or above; 4. Have directly participated in systemic treatment decision-making for patients with advanced (unresectable stage III or stage IV) solid tumors within the past 12 months; 5. Have a basic understanding of cell therapies (e.g., CAR-T, TIL, TCR-T, and NK cell therapies) and their therapeutic principles; 6. Participate voluntarily and provide electronic informed consent. * Patients Patients must meet ALL of the following criteria: 1. Aged 18 years or older; 2. Histologically or cytologically confirmed advanced solid tumor (unresectable stage III or stage IV; e.g., non-small cell lung cancer, hepatocellular carcinoma, colorectal cancer, gastric cancer, melanoma, or ovarian cancer); 3. Received at least one prior line of systemic anticancer therapy (chemotherapy, targeted therapy, immune checkpoint inhibitors, or other cellular immunotherapy) in the advanced or metastatic setting; 4. Eastern Cooperative Oncology Group (ECOG) performance status of 0-2, with adequate cognitive and physical capacity to complete the questionnaire; 5. Able to understand the questionnaire content independently or with assistance from a study coordinator; 6. Participate voluntarily and provide electronic informed consent. Exclusion Criteria: * Physicians Physicians meeting ANY of the following criteria will be excluded: 1. Individuals engaged exclusively in basic research without direct involvement in clinical patient care; 2. Individuals unable, for any reason, to understand the questionnaire content or make independent judgments. * Patients Patients meeting ANY of the following criteria will be excluded: 1. Patients who are unaware of their tumor stage or treatment status; 2. Severe cognitive impairment or psychiatric disorders that preclude comprehension of the questionnaire content or independent judgment; 3. Estimated life expectancy of less than 3 months as assessed by the treating physician, or insufficient physical capacity to complete the questionnaire; 4. Uncontrolled acute illness or other urgent medical conditions that make study participation inadvisable.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310000, China
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