New antibiotic duo takes on tough UTIs in head-to-head trial

NCT ID NCT04979806

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This study tested a new antibiotic called cefepime-zidebactam against a standard antibiotic (meropenem) in about 530 adults hospitalized with complicated urinary tract infections or kidney infections. The goal was to see if the new drug works as well and is safe. Participants received treatment for 7 to 10 days while staying in the hospital.

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Contacts and locations

Locations

  • ACE Hospital and Research Centre

    Pune, Maharashtra, 411004, India

  • Aartham Multi Super Speciality Hospital

    Ahmedabad, 380006, India

  • Accord Hospitals

    Pune, Maharashtra, 412105, India

  • Acibadem City Clinic University Multiprofile Hospital for Active Treatment Tokuda EAD

    Sofia, Bulgaria

  • Arke SMO S.A. de C.V.

    Veracruz, Mexico

  • Centro de Investigacion Clinica de Oaxaca (CICLO)

    Oaxaca City, Mexico

  • Deyang People's Hospital

    Deyang, China

  • Fakultna nemocnica Nitra

    Nitra, Slovakia

  • Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica

    Banská Bystrica, Slovakia

  • Fakultna nemocnica s poliklinikou Zilina

    Žilina, Slovakia

  • Fudan University Huashan Hospital

    Shanghai, 200040, China

  • General hospital of the PLA northern theater command

    Liaoyang, China

  • Hospital Angeles Chihuahua

    Chihuahua City, 31238, Mexico

  • Hunan Provincial People's Hospital

    Changsha, China

  • Ida-Viru Central Hospital

    Kohtla-Järve, Estonia

  • JM Research Cuernavaca

    Cuernavaca, 62290, Mexico

  • Klaipedos university hospital

    Klaipėda, LT-92288, Lithuania

  • MHAT Dobrich AD

    Dobrich, Bulgaria

  • Multiprofile Hospital for Active Teatment (MHAT) and Emergency Medicine - Pirogov

    Sofia, Bulgaria

  • Multiprofile Hospital for Active Treatment (MHAT) Sveta Anna - Varna

    Varna, Bulgaria

  • Multiprofile Hospital for Active Treatment (MHAT)- Silistra

    Silistra, Bulgaria

  • Multiprofile Hospital for Active Treatment - KANEV

    Rousse, Bulgaria

  • Multiprofile Hospital for Active Treatment - Plovdiv AD, Plovdiv

    Plovdiv, Bulgaria

  • Nemocnica Poprad, a.s. Urologicke oddeleni

    Poprad, Slovakia

  • North Estonia Medical Centre Foundation

    Tallinn, Estonia

  • ORIION Citicare Super Speciality Hospital

    Aurangabad, 431005, India

  • Pharmacology & Clinical Research

    Querétaro, Mexico

  • Republican Vilnius University hospital

    Vilnius, Lithuania

  • S&D Clinical Research, LLC

    Fort Myers, Florida, 33919, United States

  • SCM Sp. z o.o.

    Krakow, 31-559, Poland

  • Santos Research Center

    Tampa, Florida, 33615, United States

  • Shaoxing People's Hospital

    Shaoxing, China

  • South-Estonian Hospital Ltd.

    Võru, Estonia

  • Supe Hearth & Diabetes Hospital & Research Centre

    Nashik, Maharashtra, 422002, India

  • Super Speciality Hospital Government Medical College and Hospital

    Aurangabad, Maharashtra, 431004, India

  • Tartu University Hospital

    Tartu, Estonia

  • The Second Affiliated Hospital of Chongqing Medical University

    Chongqing, 400010, China

  • The Second Xiangya Hospital of Central South University

    Changsha, China

  • UMHAT Aleksandrovska Sofia - Clinic of Urology, Clinic of Anaesthesiology and Intensive Care, Clinic of Clinical Hematology

    Sofia, Bulgaria

  • UMHAT Dr. Georgi Stranski

    Pleven, Bulgaria

  • Unidad de Atención Médica e Investigación en Salud (Unamis)

    Yucatán, C.P 97000, Mexico

  • Uniwersytecki Szpital Kliniczny nr 1 im. Norberta Barlickiego w Lodzi, Oddzial Nefrologii

    Lodz, 90-153, Poland

  • Vilnius University Hospital Santaros Klinikos

    Vilnius, Lithuania

  • Vilnius city clinical hospital

    Vilnius, Lithuania

  • West China Hospital, Sichuan University

    Chengdu, 610041, China

  • West Tallinn Central Hospital

    Tallinn, Estonia

  • Wojskowy Instytut Medyczny - Panstwowy Instytut Badawczy, Klinika Chorob Wewnetrznych, Nefrologii i Dializoterapii

    Warsaw, Poland

  • Zespol Opieki Zdrowotnej w Boleslawcu

    Bolesławiec, Poland

Conditions

Explore the condition pages connected to this study.