Engineered immune cells take aim at tough blood cancers

NCT ID NCT04088890

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a new type of immune cell therapy, called CD22 CAR T cells, could be made from patients' own blood cells and safely given to adults with hard-to-treat B-cell leukemia or lymphoma. The main goals were to see if the cells could be produced successfully and to check for serious side effects. 52 participants were enrolled, and the therapy is designed to control the disease rather than cure it, as ongoing management may still be needed.

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Conditions

The condition(s) this trial relates to.

B-cell acute lymphoblastic leukemia B-cell neoplasm B-cell non-Hodgkin lymphoma diffuse large B-cell lymphoma follicular lymphoma precursor B-cell acute lymphoblastic leukemia primary mediastinal large B-cell lymphoma Richter transformation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Stanford Medical Center

    Stanford, California, 94304, United States