New pill shows promise for rare blood cancer in early trial

NCT ID NCT05141682

First seen Nov 10, 2025 · Last updated Jun 17, 2026 · Updated 34 times

Summary

This study tests an oral chemotherapy drug called CC-486 (azacitidine) in 11 adults with a rare type of leukemia (T-LGLL) that has returned or not responded to prior treatments. The goal is to find the best dose and see if the drug can shrink or control the cancer. Participants will be monitored for side effects and how long any benefits last.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • University of Virginia

    Charlottesville, Virginia, 22908, United States

Conditions

Explore the condition pages connected to this study.