Could a tailored talk therapy prevent psychosis in at-risk youth?

NCT ID NCT07188597

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a culturally adapted version of Cognitive Behavioral Therapy (CBT) for 90 young people aged 16-35 in Pakistan who show early signs of psychosis risk. The therapy aims to reduce distressing symptoms and prevent the development of full psychosis. Researchers will check if the approach is feasible and acceptable in a low-income country.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cognitive Behavioral Therapy (CBT)

What this could lead to

If successful, this could provide an effective, culturally appropriate therapy to reduce symptoms and prevent psychosis in low-resource settings.

What could go wrong

This is a small, early feasibility study (90 participants) in one country, so results may not apply elsewhere. The therapy may not work as well as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Commuity/Schools/Colleges

    RECRUITING

    Karachi, Sindh, Pakistan

  • Karwan e Hayat

    RECRUITING

    Karachi, Sindh, Pakistan