New CAR-T therapy offers hope for lymphoma patients after first-line treatment fails

NCT ID NCT04316624

First seen Feb 16, 2026 · Last updated May 12, 2026 · Updated 12 times

Summary

This early-stage study tested a new type of CAR-T cell therapy (C-CAR066) in 7 adults with diffuse large B-cell lymphoma whose cancer returned or didn't respond after a prior CAR-T treatment. The therapy targets a protein called CD20 on cancer cells. The main goals were to check safety and see if the treatment could shrink tumors. Because patients may need ongoing monitoring or additional treatments, this is considered disease control rather than a cure.

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Contacts and locations

Locations

  • Institute of Hematology & Blood Diseases Hospital

    Tianjin, 300020, China

Conditions

Explore the condition pages connected to this study.