Can a cannabis compound sharpen or dull the mind? a study puts CBG to the test

NCT ID NCT05324982

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial investigates how a single oral dose of cannabigerol (CBG), a natural compound from the cannabis plant, affects healthy adults. Over five sessions, participants receive either a placebo or one of four doses of CBG, then undergo eight hours of monitoring including blood and urine tests, heart rate and blood pressure checks, and computer-based tasks measuring attention, memory, and reaction speed. The goal is to understand CBG's safety, how the body processes it, and its short-term effects on the mind and body.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an oral cannabis compound called cannabigerol (CBG)
What this could lead to
If successful, this study could provide the first detailed data on how CBG behaves in the human body, potentially guiding future research into its medical uses.
What could go wrong
This is a very early, small study in healthy volunteers, so results may not apply to people with medical conditions. The effects of CBG are still largely unknown, and it may cause side effects like other cannabis compounds.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Behavioral Pharmacology Research Unit

    Baltimore, Maryland, 21224, United States

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