Skin gel trial offers hope for easing fragile x symptoms

NCT ID NCT04977986

Summary

This study tested whether a cannabidiol (CBD) gel applied to the skin could help reduce behavioral challenges in children and young adults with Fragile X Syndrome. Over 200 participants, aged 3 to under 30, were randomly assigned to receive either the active gel or a placebo gel for 18 weeks. The main goal was to see if the treatment was safe and if it improved symptoms like social avoidance and irritability, as reported by caregivers.

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Contacts and locations

Locations

  • Amnova Clinical Research, LLC

    Irvine, California, 92604, United States

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • Central States Research

    Tulsa, Oklahoma, 74136, United States

  • Children's National Medical center

    Washington D.C., District of Columbia, 20010, United States

  • Genetics Clinics Australia

    Melbourne, Victoria, 3161, Australia

  • Greenwood Genetic Center

    Greenville, South Carolina, 29605, United States

  • Health New Zealand - Te Whatu Ora - Wellington Hospital

    Newtown, Wellington Region, 6021, New Zealand

  • Kennedy Krieger Institute

    Baltimore, Maryland, 21205, United States

  • King's College

    London, United Kingdom

  • Lady Cilento Children's Hospital - South Brisbane

    Brisbane, Queensland, 4101, Australia

  • Leicester Clinical Research

    Leicester, United Kingdom

  • Manchester University NHS Foundation Trust

    Manchester, United Kingdom

  • Penn State Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • Phoenix Children's Hospital

    Phoenix, Arizona, 85016, United States

  • Primary Children's Hospital

    Salt Lake City, Utah, 84113, United States

  • Rare Disease Research

    Atlanta, Georgia, 30318, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • Science 37

    Culver City, California, 90230, United States

  • The Fragile X Spectrum Disorder Clinic at Icahn School of Medicine at Mount Sinai, Division of Medical Genetics

    New York, New York, 10029, United States

  • Thompson Autism Center CHOC

    Orange, California, 92868, United States

  • UC Davis Health System, MIND Institute

    Sacramento, California, 95817, United States

  • University of Edinburgh

    Edinburgh, United Kingdom

  • University of Miami

    Miami, Florida, 33136, United States

  • University of Minnesota Fragile X Clinic (Voyager Clinic)

    Minneapolis, Minnesota, 55454, United States

  • University of Mississippi

    Jackson, Mississippi, 39216, United States

  • Wellcome HRB Clinical Research Facility

    Dublin, Ireland

  • Westmead Children's Hospital

    Sydney, New South Wales, 2145, Australia

Conditions

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