Could CBD help control schizophrenia symptoms with fewer side effects?

NCT ID NCT02926859

First seen Feb 03, 2026 · Last updated May 08, 2026 · Updated 9 times

Summary

This study tests whether adding cannabidiol (CBD) to standard antipsychotic medication can help people with early schizophrenia manage their symptoms better and with fewer side effects. About 180 participants will receive either CBD or a placebo alongside their usual treatment for one year. The goal is to see if CBD helps people stay on treatment longer and improves their overall mental health.

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Contacts and locations

Locations

  • Dep. of Psychiatry and Psychotherapy, Central Institute of Mental Health

    Mannheim, Baden-Wurttemberg, 68159, Germany

  • Department of Psychiatry und Psychotherapy, University Hospital Hamburg-Eppendorf

    Hamburg, 20246, Germany

  • Department of Psychiatry, Psychotherapy, and Psychosomatics, RWTH Aachen

    Aachen, North Rhine-Westphalia, 52074, Germany

  • Dept. of Psychiatry and Psychotherapy, Charité, Campus Charité-Mitte

    Berlin, B, 10117, Germany

  • Dept. of Psychiatry and Psychotherapy, Ludwig-Maximillians-University Munich

    Munich, Bavaria, 80336, Germany

  • Dept. of Psychiatry and Psychotherapy, University Hospital of Cologne

    Cologne, North Rhine-Westphalia, 50924, Germany

Conditions

Explore the condition pages connected to this study.