Can CBD tame seizures in severe childhood epilepsy? a major trial aims to find out

NCT ID NCT07723976

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This phase 3 trial is testing whether a cannabidiol oral solution (CBD-OS) can safely reduce seizures in people aged 1 year and older with developmental and epileptic encephalopathy (DEE), a group of severe epilepsy syndromes. Participants receive either CBD or a placebo twice daily for several weeks. The study measures changes in seizure frequency and caregiver-reported improvements.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
cannabidiol oral solution (CBD-OS, JZP926-OS)
What this could lead to
If effective, this could provide a new treatment option to reduce seizures in people with developmental and epileptic encephalopathy.
What could go wrong
This is a phase 3 trial, but results may not apply to all DEE types. Side effects of CBD can include drowsiness, diarrhea, and liver enzyme changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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