New combo therapy and surgery shows promise for advanced bladder cancer

NCT ID NCT06764095

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 26 times

Summary

This study tests a standard treatment of two drugs (enfortumab vedotin and pembrolizumab) followed by surgery to remove part or all of the bladder or urinary tract in people with advanced bladder cancer that has spread. The goal is to see if this approach helps patients live longer without the cancer growing. About 75 adults with locally advanced or metastatic bladder or upper urinary tract cancer will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

Conditions

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