Engineered immune cells take aim at stubborn blood cancers in early trial

NCT ID NCT06765876

First seen Jan 12, 2026 · Last updated May 01, 2026 · Updated 23 times

Summary

This early-phase trial tests a personalized cell therapy called CART123 for adults with certain blood cancers (like acute myeloid leukemia) that have not responded to standard treatments. Each patient's own immune cells are collected, modified to target a protein called CD123 on cancer cells, and then infused back after a short chemotherapy course. The main goals are to find a safe dose and check for side effects, with 18 participants expected.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MYELODYSPLASTIC SYNDROMES (MDS) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ustav hematologie a krevni transfuze / Institute of Hematology and Blood Transfusion

    RECRUITING

    Prague, 12800, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.