New combo aims to boost remission in rare blood cancer

NCT ID NCT04263480

First seen May 14, 2026 · Last updated May 16, 2026 · Updated 1 time

Summary

This study tests whether adding carfilzomib to ibrutinib works better than ibrutinib alone for people with Waldenström's macroglobulinemia, a rare blood cancer. About 99 participants will receive either the combination or ibrutinib alone. The goal is to see if the combo leads to higher rates of complete or very good partial remission after 12 months.

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Contacts and locations

Locations

  • Alexandra Hospital

    Athens, 11528, Greece

  • Bruederkrankenhaus St. Josef

    Paderborn, 33098, Germany

  • Ev. Diakoniekrankenhaus

    Bremen, 28239, Germany

  • Gemeinschaftspraxis Mohm / Prange-Krex

    Dresden, 01307, Germany

  • Hämatologie/Onkologie München Pasing MVZ GmbH

    Munich, 81241, Germany

  • Hämatologisch-Onkologische Schwerpunktpraxis Drs. Schöttker & Pretscher

    Würzburg, 97080, Germany

  • Kath. St.-Johannes-Gesellschaft Dortmund gGmbH

    Dortmund, 44137, Germany

  • Kliniken Ostalb, Staufenklinikum Schw. Gmuend

    Mutlangen, 72557, Germany

  • MediProject Onkologisches Ambulanzzentrum Hannover

    Hanover, 30171, Germany

  • Medizinische Universität Wien

    Vienna, 1090, Austria

  • OncoResearch Lerchenfeld GmbH

    Hamburg, 22081, Germany

  • Praxis Dr. Vehling-Kaiser

    Landshut, 84130, Germany

  • Praxis für Hämatologie und Onkologie, onkologische Tagesklinik-VK&K Studien GbR

    Landshut, 84036, Germany

  • Uniklinikum Salzburg

    Salzburg, 5020, Austria

  • University Hospital Ulm

    Ulm, 89081, Germany

  • Universitätsmedizin Rostock

    Rostock, 18055, Germany

  • Vivantes Klinikum am Urban

    Berlin, 10967, Germany

Conditions

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