Could a cannabidiol drug help heal inflamed hearts?
NCT ID NCT05180240
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests whether CardiolRx, a pharmaceutical cannabidiol, can improve heart recovery in adults with acute myocarditis (heart muscle inflammation). Participants receive either CardiolRx or a placebo for 12 weeks. The study uses heart MRI scans to measure changes in heart tissue and function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
CardiolRx (cannabidiol)
What this could lead to
If it works, this could point toward a new treatment to help the heart heal better after acute myocarditis.
What could go wrong
This is a phase 2 trial with 109 participants, so results are still early and may not confirm benefit. Side effects of cannabidiol are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Barzilai Medical Center
Ashkelon, 7830604, Israel
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Beilinson Hospital, Rabin medical Center
Petah Tikva, 4941492, Israel
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CHU de Montpellier
Montpellier, 34295, France
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Centre Hospitalier Universitaire de Nîmes
Nîmes, 30029, France
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Centre Hospitalier Universitaire de Poitiers
Poitiers, France
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Chu Rangueil
Toulouse, France
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Complexo Hospitalar de Niterói
Niterói, Rio de Janeiro, 24020-096, Brazil
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Hopital Bichat Claude Bernard
Paris, France
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Hopital Louis Pradel Hospices Civils de Lyon
Bron, 69500, France
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Hospital Angelina Caron
Campina Grande do Sul, Brazil
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Hospital Felicio Rocho - Fundação Felice Rosso
Belo Horizonte, Brazil
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Hospital Moinhos de Vento
Porto Alegre, Rio Grande do Sul, 90035-001, Brazil
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Hospital Nove de Julho
São Paulo, São Paulo, 01409-002, Brazil
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Hospital Pró-Cardíaco
Rio de Janeiro, Brazil
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Hospital Regional de São José
São José, Brazil
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Hospital São Lucas
Porto Alegre, Brazil
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Hospital de Clínicas de Porto Alegre (HCPA)
Porto Alegre, Rio Grande do Sul, 90035-003, Brazil
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Hôpital Foch
Suresnes, 92150, France
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Hôpital Lariboisière - Département de Cardiologie
Paris, 75475, France
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Hôpital européen Georges-Pompidou
Paris, France
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Institut de Cardiologie hopital Pitié Salpêtrière
Paris, France
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Instituto D´Or de Pesquisa e Ensino
Rio de Janeiro, 22281-100, Brazil
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Instituto do Coração - InCor
São Paulo, Brazil
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Irmandade da Santa Casa de Misericórdia de São Paulo
São Paulo, 01223-001, Brazil
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Massachusetts General Hospital site
Boston, Massachusetts, 02114, United States
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McGill University Health Centre
Montreal, Quebec, H4A 3J1, Canada
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MedStar Heart and Vascular Institute
Washington D.C., District of Columbia, 20010, United States
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Minneapolis Heart Institute Foundation
Minneapolis, Minnesota, 55407, United States
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Nupec-Orizonti
Belo Horizonte, Minas Gerais, 30210090, Brazil
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PUC trials
Curitiba, Paraná, 80230-130, Brazil
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Shaare Zedek Medical Center
Jerusalem, 9103102, Israel
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Shamir Medical Center (Assaf Harofeh)
Zrifin, 70300, Israel
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Tel Aviv Sourasky Medical Center (Ichilov)
Tel Aviv, 6423906, Israel
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University of Alberta Hospital
Edmonton, Alberta, T6G2B7, Canada
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
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Virginia Commonwealth University
Richmond, Virginia, 23298, United States