New dual-target CAR-T therapy takes on hard-to-treat blood cancers

NCT ID NCT06986434

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests a new treatment called CAR19-BCMA CAR-T for people with certain blood cancers (plasma cell neoplasms or lymphomas/leukemias) that have returned or not responded to at least three prior treatments. The therapy uses a patient's own immune cells, modified to target two markers (CD19 and BCMA) on cancer cells. The main goals are to check safety and find the best dose, with 20 participants enrolled.

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Conditions

The condition(s) this trial relates to.

AL amyloidosis lymphoma lymphoplasmacytic lymphoma plasma cell leukemia plasma cell myeloma plasma cell neoplasm Recurrence refractory plasma cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • the Fifth Medical Center of Chinese People's Liberation Army General Hospital

    Beijing, China