First human test of 'Off-the-Shelf' cell therapy for tough blood cancers

NCT ID NCT04984356

Summary

This study tested the safety and early effectiveness of a new type of cell therapy called WU-CART-007 in adults and adolescents with T-cell leukemia or lymphoma that has come back or not responded to other treatments. The main goals were to find a safe dose and see if the therapy could help control the cancer. It involved 28 patients who had no other standard treatment options available.

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Contacts and locations

Locations

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • City of Hope

    Duarte, California, 91010, United States

  • Erasmus MC

    Rotterdam, Netherlands

  • Hospital Saint- Louis

    Paris, France

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, Australia

  • Prinses Maxima Centrum

    Utrecht, Netherlands

  • University Hospital Robert Debre

    Paris, France

  • University of Wisconsin

    Madison, Wisconsin, 53792, United States

  • Vanderbilt University

    Nashville, Tennessee, 37212, United States

  • Washington University

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.