CAR-T therapy takes on tough blood disorder in early trial

NCT ID NCT07091370

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-stage trial tests a new CAR-T cell therapy called inaticabtagene autoleucel for people with autoimmune hemolytic anemia (AIHA) that hasn't improved after at least three prior treatments. The study will enroll 12 adults and primarily check for safety and the right dose. It's a first step to see if this immune-cell therapy can help control this rare blood condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

inaticabtagene autoleucel (a CAR-T cell therapy)

What this could lead to

If it works, this could point toward a new treatment option for people with severe autoimmune hemolytic anemia who have run out of standard therapies.

What could go wrong

This is a very early, small Phase 1 trial focused on safety, not effectiveness. CAR-T therapies can cause serious side effects like cytokine release syndrome, and it may not work for this condition.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for EVANS SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

autoimmune hemolytic anemia autoimmune hemolytic anemia, cold type cold agglutinin disease Evans syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••