Engineered immune cells battle stubborn lymphoma in new trial
NCT ID NCT03105336
Summary
This study tested whether a treatment called axicabtagene ciloleucel, a type of CAR-T cell therapy, could help people with slow-growing non-Hodgkin lymphoma that had come back or stopped responding to other treatments. It involved 159 participants whose cancer had progressed after at least two prior lines of therapy. The approach involved collecting a patient's own immune cells, genetically modifying them to better target cancer, and then infusing them back into the patient.
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Contacts and locations
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Locations
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Banner MD Anderson Cancer Center
Gilbert, Arizona, 85234, United States
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Centre Hospitalier Lyon Sud
Pierre-Bénite, 69495, France
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Centre Hospitalier Régional Universitaire de Lille
Lille, 59037, France
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Columbia University Medical Center
New York, New York, 10032, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Fox Chase Cancer Center
Philadelphia, Pennsylvania, 19111, United States
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Fred Hutchinson Cancer Research Center
Seattle, Washington, 98109, United States
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Georgetown Lombardi Comprehensive Cancer Center
Washington D.C., District of Columbia, 20007, United States
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H Lee Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Hackensack University Medical Center - John Theurer Cancer Center
Hackensack, New Jersey, 07601, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Ohio State University Medical Center
Cleveland, Ohio, 44106, United States
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Sarah Cannon Research Institute
Nashville, Tennessee, 37203, United States
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UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania, 15232, United States
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USC Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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University of California Los Angeles
Los Angeles, California, 90095, United States
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University of Miami Hospital and Clinics
Miami, Florida, 33136, United States
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University of Rochester Medical Center (URMC)
Rochester, New York, 14642, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
Conditions
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